Results 31 to 40 of about 34,736 (254)

Securin Is Not Required for Chromosomal Stability in Human Cells [PDF]

open access: yes, 2005
Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest.
Azofeifa   +32 more
core   +4 more sources

Management of E. coli sister chromatid cohesion in response to genotoxic stress

open access: yesNature Communications, 2017
Homologous recombination of DNA lesions in bacteria involves sister chromatid pairing. Here, the authors show that RecN promotes contacts between sister chromatids and facilitates repair.
Elise Vickridge   +4 more
doaj   +1 more source

DNA damage in the kidney tissue cells of the fish Rhamdia quelen after trophic contamination with aluminum sulfate

open access: yesGenetics and Molecular Biology, 2015
Even though aluminum is the third most common element present in the earth's crust, information regarding its toxicity remains scarce. It is known that in certain cases, aluminum is neurotoxic, but its effect in other tissues is unknown.
Tatiane Klingelfus   +3 more
doaj   +1 more source

Relationship between chromatin bridges in anaphase and chromosomal aberrations induced by TMP+UVA (365 nm) in CHO cells [PDF]

open access: yes, 1997
In a recent paper, the hypothesis of 'conservative pairing' between complementary DNA strands belonging to both sister chromatids has been proposed as a phenomenon that could account for, at least in part, sister chromatid pairing in late G(2)/mitosis ...
Botta, R, Gustavino B
core   +1 more source

In Favor of Establishment: Regulation of Chromatid Cohesion in Plants

open access: yesFrontiers in Plant Science, 2017
In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas   +4 more
doaj   +1 more source

Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]

open access: yes, 2013
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
A Chavez   +115 more
core   +8 more sources

Cyclin A2 Is Required for Sister Chromatid Segregation, But Not Separase Control, in Mouse Oocyte Meiosis

open access: yesCell Reports, 2012
In meiosis, two specialized cell divisions allow the separation of paired chromosomes first, then of sister chromatids. Separase removes the cohesin complex holding sister chromatids together in a stepwise manner from chromosome arms in meiosis I, then ...
Sandra A. Touati   +10 more
doaj   +1 more source

Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis. [PDF]

open access: yesPLoS Biology, 2010
Recombination between homologous chromosomes of different parental origin (homologs) is necessary for their accurate segregation during meiosis. It has been suggested that meiotic inter-homolog recombination is promoted by a barrier to inter-sister ...
Tamara Goldfarb, Michael Lichten
doaj   +1 more source

Principles of meiotic chromosome assembly revealed in S. cerevisiae [PDF]

open access: yes, 2019
During meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear.
A Goloborodko   +69 more
core   +2 more sources

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

open access: yeseLife, 2017
Homologous recombination involving sister chromatids is the most accurate, and thus most frequently used, form of recombination-mediated DNA repair. Despite its importance, sister chromatid recombination is not easily studied because it does not result ...
Clémence Claussin   +7 more
doaj   +1 more source

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