Securin Is Not Required for Chromosomal Stability in Human Cells [PDF]
Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest.
Azofeifa +32 more
core +4 more sources
Management of E. coli sister chromatid cohesion in response to genotoxic stress
Homologous recombination of DNA lesions in bacteria involves sister chromatid pairing. Here, the authors show that RecN promotes contacts between sister chromatids and facilitates repair.
Elise Vickridge +4 more
doaj +1 more source
Even though aluminum is the third most common element present in the earth's crust, information regarding its toxicity remains scarce. It is known that in certain cases, aluminum is neurotoxic, but its effect in other tissues is unknown.
Tatiane Klingelfus +3 more
doaj +1 more source
Relationship between chromatin bridges in anaphase and chromosomal aberrations induced by TMP+UVA (365 nm) in CHO cells [PDF]
In a recent paper, the hypothesis of 'conservative pairing' between complementary DNA strands belonging to both sister chromatids has been proposed as a phenomenon that could account for, at least in part, sister chromatid pairing in late G(2)/mitosis ...
Botta, R, Gustavino B
core +1 more source
In Favor of Establishment: Regulation of Chromatid Cohesion in Plants
In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas +4 more
doaj +1 more source
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
A Chavez +115 more
core +8 more sources
In meiosis, two specialized cell divisions allow the separation of paired chromosomes first, then of sister chromatids. Separase removes the cohesin complex holding sister chromatids together in a stepwise manner from chromosome arms in meiosis I, then ...
Sandra A. Touati +10 more
doaj +1 more source
Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis. [PDF]
Recombination between homologous chromosomes of different parental origin (homologs) is necessary for their accurate segregation during meiosis. It has been suggested that meiotic inter-homolog recombination is promoted by a barrier to inter-sister ...
Tamara Goldfarb, Michael Lichten
doaj +1 more source
Principles of meiotic chromosome assembly revealed in S. cerevisiae [PDF]
During meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear.
A Goloborodko +69 more
core +2 more sources
Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq
Homologous recombination involving sister chromatids is the most accurate, and thus most frequently used, form of recombination-mediated DNA repair. Despite its importance, sister chromatid recombination is not easily studied because it does not result ...
Clémence Claussin +7 more
doaj +1 more source

