Results 111 to 120 of about 659,276 (230)
Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. [PDF]
, 2019 The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly ...
Bandyopadhyay, Guatam K +3 more
core
ENANTIOMETRIC SEPARATION OF SITAGLIPTIN IN A FIXED DOSE COMBINATION FORMULA OF SITAGLIPTIN AND METFORMIN BY A CHIRAL LIQUID CHROMATOGRAPHIC METHOD [PDF]
, 2019 Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
Jaishetty, Nagadeep +2 more
core +1 more source
Pathology and glia type specific changes of the DPP4 activity in the spinal cord contributes to the development and maintenance of hyperalgesia and shapes opioid signalling in chronic pain states [PDF]
, 2017 Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various chronic pain states, and remain difficult to treat.
Alpár, Alán +14 more
core
Method Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form [PDF]
Method Development and Validation of RP-HPLC for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form was developed using Qualisil C18 BDS Column(150×4.5mm,5µ) as stationary phase and Potassium dihydrogen phosphate and Acetonitrile in a ratio 60:
N. Gayathri, K. Prabhakaran, A. Naveen, M. Kavinilavu, S. Maheshboopathi, M. Manikandan, M. Kaviyarasu, N. Astalakshmi, M. Surendrakumar
core +1 more source
Oligomers-model building in protonation equilibria of sitagliptin
Open Chemistry, 2013 Meloun Milan +3 more
doaj +1 more source