Results 171 to 180 of about 659,276 (230)

RISING STARS: Effects of a GLP-1 receptor polymorphism on responses to liraglutide. [PDF]

open access: yesJ Endocrinol
Mashayekhi M   +12 more
europepmc   +1 more source

In vitro study and pharmacokinetic evaluation of sitagliptin phosphate enantiomers in rat plasma.

Bioanalysis, 2023
Background: A chiral HPLC technique was developed to determine sitagliptin phosphate enantiomers in rat plasma in compliance with US FDA regulations. Methods & results: The technique used a Phenomenex column with a mobile phase consisting of a 60:35:5 (v/
T. Spandana   +2 more
semanticscholar   +3 more sources

Pharmacokinetics and relative bioavailability of sitagliptin hydrochloride and sitagliptin phosphate tablets formulations: a randomized, open-label, crossover study in healthy male volunteers

Generics and Biosimilars Initiative Journal, 2023
Introduction/Study Objectives: The present study aimed to evaluate the comparative bioavailability of a new generic sitagliptin formulation. Methods: This was an open label, randomized, balanced, two-sequence, two-treatment, two-period, single oral dose,
C. W. Leong   +9 more
semanticscholar   +2 more sources

Headspace gas chromatography for the determination of Isopropylamine in sitagliptin phosphate

Analytical Chemistry Letters
The detection and control of residual solvents directly affect the product quality and safety. Isopropylamine is one of the raw materials of sitagliptin phosphate and so far its detection has not been reported.
Xiao Hua Zhang, Zong Wen Pang
semanticscholar   +2 more sources

Formulation and Evaluation of Fast Dissolving Oral Film of Sitagliptin Phosphate by Solvent Casting Method

open access: yesInternational Journal of Ayurveda and Pharma Research
The primary objective of this study was to develop sitagliptin phosphate oral films that dissolve quickly in order to treat diabetic mellitus. The solvent casting method was employed to make the sitagliptin phosphate films that dissolve quickly.
V. Sruthi   +4 more
semanticscholar   +2 more sources

Pharmacokinetic bioequivalence of sitagliptin phosphate tablet formulations: a randomized, open-label, crossover study in healthy volunteers

Generics and Biosimilars Initiative Journal, 2023
Introduction/Study Objectives: The aim of the current study is to assess the rate and extent of absorption of a test and reference formulation containing sitagliptin.
C. W. Leong   +11 more
semanticscholar   +2 more sources

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