Results 111 to 120 of about 383,013 (128)

Sitagliptin phosphate ameliorates chronic inflammation in diabetes mellitus via modulating macrophage polarization [PDF]

Frontiers in Endocrinology
AimTo investigate the effect and mechanism of Sitagliptin phosphate on inflammation and macrophage polarization in a mouse model of type 2 diabetes.MethodsIn vitro, Raw264.7 cells were cultured with a high concentration of glucose (HG) and sitagliptin ...
Yalong Li
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

A highly sensitive LC-MS/MS method for the determination and quantification of a recently identified N -nitrosamine impurity in the sitagliptin phosphate monohydrate active pharmaceutical ingredient

Analytical Methods, 2023
A fully validated LC-MS/MS method was developed for quantification of 7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (NTTP) in sitagliptin phosphate monohydrate at LOQ of 0.098 ppm.
Zhen Wang, Shujun Hu, Xiaoying Wu, Zuwei He, Chunlong Ke, Miaomiao Hu   +5 more
openaire   +2 more sources

Liquid chromatographic determination of sitagliptin either alone or in ternary mixture with metformin and sitagliptin degradation product

Talanta, 2011
Two reversed-phase liquid chromatographic (RP-LC) methods have been developed for the determination of sitagliptin phosphate monohydrate (STG). The first method comprised the determination of STG alone in bulk and plasma; and in its pharmaceutical ...
Ehab F Elkady, Bassam M. Ayoub, Ramzia El-Bagary   +2 more
exaly   +1 more source

A NEW BIOANALYTICAL METHOD DEVELOPMENT & VALIDATION FOR SIMULTANEOUS ESTIMATION OF METFORMIN HYDROCHLORIDE AND SITAGLIPTIN PHOSPHATE MONOHYDRATE IN HUMAN PLASMA BY USING RP-HPLC

INDIAN DRUGS, 2014
A new RP-HPLC method for the quantitative determination of metformin and sitagliptin in human plasma was developed and validated as per US-FDA guidelines. The drug was spiked in the plasma and extracted with mobile phase by precipitation method. The extracted analyte was injected into Symmetry C18 (4.6 x 150 mm, 3.5μm, Make: XTerra) or equivalent ...
S. A Kumar, M Debnath, J. V. L. N. S Rao, G Sankar   +3 more
openaire   +1 more source

Crystal structure of sitagliptin dihydrogen phosphate monohydrate, C ₁₆ H ₁₆ F ₆ N ₅ O(H ₂ PO ₄ )(H ₂ O)

Powder Diffraction, 2015
The crystal structure of sitagliptin dihydrogen phosphate monohydrate (sometimes referred to as sitagliptin phosphate monohydrate) has been solved and refined using synchrotron X-ray powder diffraction data, and optimized using density functional techniques. Sitagliptin dihydrogen phosphate monohydrate crystallizes in space group
James A. Kaduk, Kai Zhong, Amy M. Gindhart, Thomas N. Blanton   +3 more
openaire   +1 more source

Development and Validation of a RP-HPLC Method for the Simultaneous Estimation of Metformin Hydrochloride, Sitagliptin Phosphate and Dapagliflozin Monohydrate in Fixed-Dose Combination Tablets

International Journal of Drug Delivery Technology
An easy, specific, sensitive and reproducible RP-HPLC method has been developed and validated successfully for simultaneous quantitation of Metformin hydrochloride, Sitagliptin phosphate and Dapagliflozin monohydrate from tablet formulation. Chromatographic separation was performed on a C18 column under isocratic conditions using 0.02 M KH₂PO₄ buffer ...
Himanta Biswa Saikia, Bipul Nath, Junmoni Kalita, Tanniru Rajeswari, Anju Das, Tanmay Sarma, Sourin Sarma   +6 more
openaire   +1 more source

Understanding the influence of thermal cycles on the stability of metformin HCl in presence of Sitagliptin phosphate monohydrate and polyvinyl alcohol

Journal of Thermal Analysis and Calorimetry, 2023
Rajkumar Malayandi, Adarsh Malgave, Vinod Gaikwad, Ramalingam Peraman, Dande Aishwarya, V. Ravichandiran   +5 more
openaire   +1 more source

A highly sensitive LC-MS/MS method for the determination and quantification of a recently identified N-nitrosamine impurity in the sitagliptin phosphate monohydrate active pharmaceutical ingredient†

Analytical Methods, 2023
Zhen Wang
exaly  

Exploiting synergistic effects of brittle and plastic excipients in directly compressible formulations of sitagliptin phosphate and sitagliptin hydrochloride

Pharmaceutical Development and Technology, 2022
Daniel Zakowiecki, Tobias Hess
exaly  

Environmentally friendly protocol for the determination of sitagliptin phosphate in pharmaceutical preparations and biological fluids using l-tyrosine as a fluorescence probe

Luminescence, 2023
Muhammad N Khan
exaly