Results 91 to 100 of about 446,158 (283)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimization of RNA concentration for genome editing by CRISPR in rabbit zygotes [PDF]

, 2016
Site-specific genetic modification aiming to delete (knock-out) a gene provides an unequivocal answer to elucidate the function of such particular gene in the whole organism.
Avilés, M., Bermejo Alvárez, P., Fonseca Baldís, N., García Rebollar, Pilar, Gutiérrez Adán, A., Lorenzo, P.L.   +5 more
core  

Novel Tailoring of Ternary ZnS‐MXene‐TiO2 Nanocomposite Heterojunction and Its Tunable Electrochemical Properties With Enhanced Photocatalytic Degradation

Advanced Engineering Materials, EarlyView.
ZnS‐MXene‐TiO2 nanocomposite heterojunction for photocatalytic decomposition of this methylene blue dye (MB) greatly improves light absorption, charge separation, and active site area. Two‐dimensional MXene forms nanocomposites by easily combining them with 0D (quantum dots), 1D (tube and wire), 2D (plane and sheet), and 3D (particle and lamellar ...
Latiful Kabir, Dohyun Kim, Minho Song, Jae Doc Na, Young Jun Joo, Kwang Youn Cho, Karna Wijaya, Won‐Chun Oh   +7 more
wiley   +1 more source

Estimating selection pressures on HIV-1 using phylogenetic likelihood models [PDF]

, 2008
Human immunodeficiency virus (HIV-1) can rapidly evolve due to selection pressures exerted by HIV-specific immune responses, antiviral agents, and to allow the virus to establish infection in different compartments in the body. Statistical models applied
Anisimova, Bailey, Embretson, Felsenstein, Goldman, Guindon, Ho, Huelsenbeck, Huelsenbeck, Kosakovsky Pond, Kosakovsky Pond, Kosakovsky Pond, Kosakovsky Pond, Kosakovsky Pond, Kosakovsky Pond, Kosakovsky Pond, Mansky, Massingham, Mayer-Hamblett, Muse, Nielsen, Novitsky, Pantaleo, Perelson, Perelson, Poon, Richman, Robinson, Rodrigue, Saitou, Schadt, Scheffler, Self, Seoighe, Shriner, Smith, Sugiura, Suzuki, Wei, Whelan, Whitley, Williamson, Yang, Yang, Yang, Yang, Yang, Zhuang   +47 more
core   +1 more source

Fast‐Responding O2 Gas Sensor Based on Luminescent Europium Metal‐Organic Frameworks (MOF‐76)

Advanced Functional Materials, EarlyView.
Luminescent MOF‐76 materials based on Eu(III) and mixed Eu(III)/Y(III) show rapid and reversible changes in emission intensity in response to O2 with very short response times. The effect is based on triplet quenching of the linker ligands that act as photosensitizers. Average emission lifetimes of a few milliseconds turn out to be mostly unaffected by
Zhenyu Zhao, Christian Weinberger, Jakob Steube, Matthias Bauer, Martin Brehm, Michael Tiemann   +5 more
wiley   +1 more source

Functional Analysis of the Acinetobacter baumannii XerC and XerD Site-Specific Recombinases: Potential Role in Dissemination of Resistance Genes

Antibiotics, 2020
Modules composed of a resistance gene flanked by Xer site-specific recombination sites, the vast majority of which were found in Acinetobacter baumannii, are thought to behave as elements that facilitate horizontal dissemination. The A.
David L. Lin, German M. Traglia, Rachel Baker, David J. Sherratt, Maria Soledad Ramirez, Marcelo E. Tolmasky   +5 more
doaj   +1 more source

Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes [PDF]

, 2016
Human cytomegalovirus (HCMV) infects most of the population worldwide, persisting throughout the host's life in a latent state with periodic episodes of reactivation.
Atkinson, Claire, Balloux, Francois, Breuer, Judith, Brown, Amanda C., Brown, Julianne R., Christiansen, Mette T., Clark, Duncan A., Depledge, Daniel P., Einer-Jensen, Katja, Griffiths, Paul D., Holdstock, Jolyon, Lassalle, Florent, Milne, Richard S.B., Reeves, Matthew B., Schutten, Martin, Tutill, Helena J., van Loenen, Freek B., Verjans, Georges M.G.M., Williams, Rachel J.   +18 more
core   +1 more source

Selective and Precise Editing of Digital Polymers Through Parallel or Series Toehold‐Mediated Strand Displacement

Advanced Functional Materials, EarlyView.
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski, Cyril Antheaume, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +1 more source

Auto‐Generated Valence States in Electrocatalysts for Boosting Oxygen and Hydrogen Evolution Kinetics in Alkaline Water/Alkaline Seawater/Simulated Seawater/Natural Seawater

Advanced Functional Materials, EarlyView.
This review systematically highlights the latest achievements in mixed‐valence states relevant to hydrogen and oxygen evolution reactions, providing essential insights into future directions and methods for large‐scale practical implementation. This critical review is expected to provide an overview of recent advancements in diverse valence‐state metal
Jitendra N. Tiwari, Gokul Bhaskaran, Krishan Kumar, Yun Suk Huh, Young‐Kyu Han   +4 more
wiley   +1 more source

Fractional Reaction-Diffusion Equation

, 2003
A fractional reaction-diffusion equation is derived from a continuous time random walk model when the transport is dispersive. The exit from the encounter distance, which is described by the algebraic waiting time distribution of jump motion, interferes ...
Seki, Kazuhiko, Tachiya, M., Wojcik, Mariusz   +2 more
core   +1 more source