Results 81 to 90 of about 446,158 (283)
Knotted and Linked Products of recombination on T(2,n)#T(2,m) Substrates [PDF]
, 2013 We develop a topological model of site-specific recombination that applies to substrates which are the connected sum of two torus links of the form T(2,n)#T(2,m).
Flapan, Erica +4 more
core +4 more sources
Topological Selectivity in Xer Site-Specific Recombination [PDF]
Cell, 1997 The product topology of Xer-mediated site-specific recombination at plasmid sites has been determined. The product of deletion at pSC101 psi is a right-handed antiparallel 4-noded catenane. The ColE1 cer deletion product has an identical topology, except that only one pair of strands is exchanged.
Colloms, S, Bath, J, Sherratt, D
openaire +3 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
The unconventional Xer recombination machinery of Streptococci/Lactococci.
PLoS Genetics, 2007 Homologous recombination between circular sister chromosomes during DNA replication in bacteria can generate chromosome dimers that must be resolved into monomers prior to cell division.
Pascal Le Bourgeois +8 more
doaj +1 more source
Microcin H47 system: an Escherichia coli small genomic island with novel features. [PDF]
PLoS ONE, 2011 Genomic islands are DNA regions containing variable genetic information related to secondary metabolism. Frequently, they have the ability to excise from and integrate into replicons through site-specific recombination.
María F Azpiroz +2 more
doaj +1 more source
Population Improvement Through Recurrent Selection in Rice. Prospect for Maker Assisted Recurrent Selection and Genome-Wide Selection. W011 [PDF]
, 2012 Since 1992, we have been carrying out an upland rice breeding program for Latin American and the Caribbean based on the improvement of synthetic populations of broad genetic diversity through recurrent selection (RS).
Ahmadi, Nourollah +8 more
core
Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion. [PDF]
, 2013 Serine recombinases are often tightly controlled by elaborate, topologically-defined, nucleoprotein complexes. Hin is a member of the DNA invertase subclass of serine recombinases that are regulated by a remote recombinational enhancer element containing
Chang, Yong +4 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
BMC Biotechnology, 2010 Background Cre-mediated site-specific integrative recombination in mouse embryonic stem (ES) cells is a useful tool for genome engineering, allowing precise and repeated site-specific integration. To promote the integrative reaction, a left element/right
Araki Masatake +3 more
doaj +1 more source
Adaptive evolution is substantially impeded by Hill–Robertson interference in Drosophila [PDF]
, 2015 Hill–Robertson interference (HRi) is expected to reduce the efficiency of natural selection when two or more linked selected sites do not segregate freely, but no attempt has been done so far to quantify the overall impact of HRi on the rate of adaptive ...
Adam Eyre-Walker +18 more
core +2 more sources