Results 101 to 110 of about 6,102,865 (304)

Optimization of Structural Design in Steel Buildings Based on the Site-Specific Design Spectra of the Mexico Seismic Regulations

open access: yesGeosciences
Seismic risk management in urban areas requires accurate prediction of the expected seismic hazard. The seismic design standards in the world provide the seismic design spectra (DS).
Juan Antonio Ramos-Sánchez   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Revision of the 1844 Palestrina earthquake following the recovery of an unpublished document

open access: yesAnnals of Geophysics, 1998
The paper presented originates from the recovery of an unpublished document that reports estimated damage in the city of Palestrina (Central Italy) following the 1844 earthquake.
R. Di Giovambattista   +3 more
doaj   +1 more source

Social Networks Sites : Usage and Effects

open access: yesJournal of Educational and Psychological Studies, 2013
The aim of this paper is to explore the students’ use of social networks sites (SNSs) and its effects on students’ achievement. A questionnaire using a Liker type scale was distributed to a sample of 120 undergraduate students who participated in the study. The results show that students use SNSs for social matters more than for academic purposes.
openaire   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Site effect evaluation for Culiacan, Sinaloa, Mexico

open access: yesGeofísica Internacional
Using the spectral ratio technique (HVSR), we performed an analysis of 120 seismic noise records obtained at different points distributed throughout the city of Culiacán, Sinaloa, México.
Tonatiuh Dominguez Reyes   +1 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Modulation-assisted tunneling in laser-fabricated photonic Wannier-Stark ladders

open access: yes, 2015
We observe Wannier-Stark localization in curved photonic lattices, realized using arrays of evanescently coupled optical waveguides. By correctly tuning the strength of inter-site coupling in the lattice, we observe that Wannier-Stark states become ...
Andersson, Erika   +6 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

How about integration: the impact of online activities on store satisfaction and loyalty [PDF]

open access: yes
Although there has been widespread support for the concept of integrating the Internet with other channels, relatively little empirical research has been conducted in this area.
Teerling, Marije L.
core   +1 more source

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