Results 111 to 120 of about 6,102,865 (304)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Tissue Harvesting Site Effect on the Canine Adipose Stromal Vascular Fraction Quantity and Quality. [PDF]

open access: yesAnimals (Basel), 2021
Hendawy H   +9 more
europepmc   +1 more source

Diffusion-Annihilation in the Presence of a Driving Field

open access: yes, 1995
We study the effect of an external driving force on a simple stochastic reaction-diffusion system in one dimension. In our model each lattice site may be occupied by at most one particle.
Burgers J M   +21 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

考虑震源不确定性的近断层高山峡谷场地地震动变异性分析

open access: yesDizhen xuebao
由于震源不确定性客观存在且对近地表地震动特性产生显著影响,尝试将乘子降维法应用至考虑震源不确定性的近断层复杂场地地震动变异性求解,将不确定性分析问题转换为有限次确定性分析,获得与蒙特卡洛模拟一致的地震动参数统计矩,其中单次确定性分析采用边界元法模拟断层破裂—传播路径—场地放大的整个物理过程。基于乘子降维法,以近走滑断层高山峡谷场地为例,分析了在近断层效应、场地效应和震源不确定性三者耦合作用下的场地地震动峰值加速度(PGA)、峰值速度(PGV)的空间分布变异性,以及关键地表点谱加速度(SA)的统计值 ...
Sibo Meng   +4 more
doaj   +1 more source

Earthquake Disaster Mitigation Mapping By Modeling of Land Layer and Site Effect Zone in The Kota Baru of South Lampung

open access: yesJurnal Ilmiah Pendidikan Fisika Al-Biruni, 2019
Kota Baru is the satellite city of Bandar Lampung. The city is prepared for the expansion of the city of Bandar Lampung. Zonation map of earthquake risk is required for Kota Baru due to its location within the reach of earthquake energy of Semangko ...
Nandi Haerudin   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A theoretical study of the cluster glass-Kondo-magnetic disordered alloys

open access: yes, 2009
The physics of disordered alloys, such as typically the well known case of CeNi1-xCux alloys, showing an interplay among the Kondo effect, the spin glass state and a magnetic order, has been studied firstly within an average description like in the ...
Amit   +19 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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