Results 31 to 40 of about 6,118,344 (310)

Pharmacokinetic models for propofol-defining and illuminating the devil in the detail [PDF]

open access: yes, 2009
The recently introduced open-target-controlled infusion (TCI) systems can be programmed with any pharmacokinetic model, and allow either plasma- or effect-site targeting. With effect-site targeting the goal is to achieve a user-defined target effect-site
Absalom, A.R.   +3 more
core   +2 more sources

地震动场地调整系数研究

open access: yesDizhen xuebao, 2022
回顾总结了近20年国内外关于地震动场地调整系数的主要研究成果,重点分析强震动观测和数值理论方法在考虑场地条件对地震动参数影响方面的效果,总结各类方法的适用性和优缺点,结合国内外相关规范条文对比分析国内外的主要成果,得出我国软土的场地调整系数值小于国际水平,并进一步分析了造成这种差异的原因。最后基于目前国际地震区划工作的发展趋势以及各行业相关规范的新技术需求,对新一代区划图的研究工作进行了展望。
Jingru Yan, Yushan Zhang, Wenliang Kan
doaj   +1 more source

Seismic damage and geological heterogeneity in Rome's Colosseum area: are they related?

open access: yesAnnals of Geophysics, 1995
According to the historical sources, the Colosseum suffered several types of damage related to earthquakes. In particular, the damage is mostly concentrated in the southern portion of the amphitheater where the study of the geological features shows the ...
M. Parotto   +3 more
doaj   +1 more source

Two-dimensional nonlinear seismic response analysis for seabed site effect assessment in Jintang Strait

open access: yesYantu gongcheng xuebao, 2021
Ensuring the safety of coastal and offshore projects subjected to strong earthquakes is a major engineering challenge. A two-dimensional nonuniform gridding and fine finite element model for the seabed cross-section site in Jintang Strait is established ...
CHEN Guo-xing 1, 2, YUE Wen-ze 1, 2, RUAN Bin 3, WANG Yan-zhen 1, 2
doaj   +1 more source

Effects of folding on metalloprotein active sites [PDF]

open access: yesProceedings of the National Academy of Sciences, 1997
Experimental data for the unfolding of cytochrome c and azurin by guanidinium chloride (GuHCl) are used to construct free-energy diagrams for the folding of the oxidized and reduced proteins. With cytochrome c , the driving force for folding the reduced protein is larger than that for the ...
Winkler, Jay R.   +4 more
openaire   +2 more sources

Leveraging Social Media to Promote EvidenceBased Continuing Medical Education [PDF]

open access: yes, 2017
Importance New dissemination methods are needed to engage physicians in evidence-based continuing medical education (CME). Objective To examine the effectiveness of social media in engaging physicians in non-industry-sponsored CME.
Flynn, Simone   +5 more
core   +4 more sources

Dynamic response of stepped loess slopes in embankment under running loads of high-speed train

open access: yesYantu gongcheng xuebao, 2021
In order to study the dynamic response of loess slopes under high-speed train loads and evaluate their influence on the stability of the loess slopes, the vibration characteristics of loess slope site under train loads are analyzed in time domain and ...
YAN Wu-jian 1, 2, ZHENG Hai-zhong 1, CHE Ai-lan 3, WANG Ping 1, 2, TIAN Xin-xin 1
doaj   +1 more source

Vulnerability and Site Effects in Earthquake Disasters in Armenia (Colombia). I—Site Effects [PDF]

open access: yesGeosciences, 2018
The city of Armenia, Colombia has been repeatedly subjected to moderate magnitude earthquakes. Damage in that city for the 1999 (Mw6.2) event was disproportionate (maximum observed EMS-92 intensity of IX), even considering the small epicentral distance (18 km). Two main factors have been invoked: Site effects and vulnerability of the building stock. We
Francisco J. Chávez-García   +3 more
openaire   +2 more sources

Effect of different site energies on polaronic properties

open access: yes, 2005
Using the perturbation method based on a variational phonon basis obtained by the modified Lang-Firsov (MLF) transformation, the two-site single polaron Holstein model is studied in presence of a difference in bare site energies ($\epsilon_d$=$\epsilon_2$
A. N. Das   +28 more
core   +2 more sources

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP [PDF]

open access: yes, 2000
The 3' ends of most eukaryotic pre-mRNAs are generated by 3' endonucleolytic cleavage and subsequent polyadenylation. 3'-end formation can be influenced positively or negatively by various factors.
Vagner, S.   +4 more
core   +1 more source

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