Results 81 to 90 of about 6,102,865 (304)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Site Effects and Damage Patterns [PDF]
A set of observations on site effects and damage patterns from the Mw 8.8 Maule, Chile, earthquake is presented, focusing on identification of structural damage variability associated with nonuniform soil conditions and subsurface geology. Observations are reported from: (1) the City of Santiago de Chile (Américo Vespucio Norte Ring Highway, Ciudad ...
Assimaki, Dominic +5 more
openaire +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
We study two moderate earthquakes that occurred offshore the State of Veracruz, in the southwestern Gulf of Mexico, on 29 October 2009 (Mw 5.7) and 4 August 2021 (Mw 4.8).
Arturo Iglesias Mendoza +7 more
doaj +1 more source
The optimal effect-site concentration of remifentanil to attenuate the pain caused by propofol [PDF]
BackgroundThe injection pain of propofol is a frequent and well-known adverse effect. This study was designed to determine the optimal effect-site concentration of remifentanil for minimizing injection pain during induction with propofol.MethodsA total ...
Jong-Yeon Lee +5 more
doaj +1 more source
Effect of B-site Dopants on Magnetic and Transport Properties of LaSrCoRuO$_6$
Effect of Co, Ru and Cu substitution at B and B' sites on the magnetic and transport properties of LaSrCoRuO$_6$ have been investigated. All the doped compositions crystallize in the monoclinic structure in the space group $P2_1/n$ indicating a double ...
A. Das +25 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
2021年5月21日漾濞MS6.4地震极震区地形效应对地震动特性的影响
基于对2021年5月21日漾濞MS6.4地震微观震中秀岭村进行的震害调查,利用流动观测地形台阵观测资料,分析了地形效应对地震动特性的影响。结果表明,若地震波垂直山脉走向入射,陡坡会放大地震波的高频部分,且不同高程处,山脉垂向低频差异较大,山脉走向低频差异较小。利用谱衰减法计算高频衰减参数的场地影响项κ0,分析了水平和竖向分量的κ0与场地软弱程度和卓越频率的相关性,其结果表明,在小尺度范围内,水平分量和竖向分量的κ0均具有较强的空间不均匀性。
Libao Zhang +6 more
doaj +1 more source
Here we present the calculations of incoherent current flowing through the two-site molecular device as well as the DNA-based junction within the rate-equation approach. Few interesting phenomena are discussed in detail.
A. Aviram +44 more
core +1 more source

