Results 81 to 90 of about 6,081,189 (307)
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Fano-Kondo effect in a two-level system with triple quantum dots: shot noise characteristics
We theoretically compare transport properties of Fano-Kondo effect with those of Fano effect. We focus on shot noise characteristics of a triple quantum dot (QD) system in the Fano-Kondo region at zero temperature, and discuss the effect of strong ...
Mahan G D +5 more
core +1 more source
Non-magnetic B-site Impurities Induce Ferromagnetic Tendencies in CE Manganites [PDF]
Using a two-orbital model and Monte Carlo simulations, we investigate the effect of nonmagnetic B-site substitution on half-doped CE-type manganites. The lattice defects induced by this substitution destabilize the CE phase, which transforms into (1) the
Elbio Dagotto +5 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Site Effects and Damage Patterns [PDF]
A set of observations on site effects and damage patterns from the Mw 8.8 Maule, Chile, earthquake is presented, focusing on identification of structural damage variability associated with nonuniform soil conditions and subsurface geology. Observations are reported from: (1) the City of Santiago de Chile (Américo Vespucio Norte Ring Highway, Ciudad ...
Assimaki, Dominic +5 more
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
由于震源不确定性客观存在且对近地表地震动特性产生显著影响,尝试将乘子降维法应用至考虑震源不确定性的近断层复杂场地地震动变异性求解,将不确定性分析问题转换为有限次确定性分析,获得与蒙特卡洛模拟一致的地震动参数统计矩,其中单次确定性分析采用边界元法模拟断层破裂—传播路径—场地放大的整个物理过程。基于乘子降维法,以近走滑断层高山峡谷场地为例,分析了在近断层效应、场地效应和震源不确定性三者耦合作用下的场地地震动峰值加速度(PGA)、峰值速度(PGV)的空间分布变异性,以及关键地表点谱加速度(SA)的统计值 ...
Sibo Meng +4 more
doaj +1 more source
This study proposes a model of a totally asymmetric simple exclusion process on a single channel lane with functions of site-assignments along the pitlane.
Nishinari, Katsuhiro +2 more
core +1 more source

