Results 151 to 160 of about 2,631,711 (310)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Oak Ridge Reservation K-25 facility : contaminated off-site groundwater
In 1942, the federal government established the Oak Ridge Reservation (ORR) in Anderson and Roane Counties in eastern Tennessee as part of the Manhattan Project to research, develop, and produce special radioactive materials for nuclear weapons.
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Welfare measurement bias in household and on-site surveying of water-based recreation : an application to Lake Sevan, Armenia [PDF]
Studies comparing household surveys with on-site interceptor surveys have typically accounted for over-sampling avid users in the on-site interceptor surveys (that is, endogenous stratification).
Meisner, Craig +2 more
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Site effects Estimation and Source_Scaling Dynamics for Local Earthquakes at Mt. Vesuvius, Italy
, 2006 Local microearthquakes were used to estimate site effects and source dynamic-scaling characteristics at Mt. Vesuvius, Italy. The selected data set is composed of low magnitude events (1.1 £ Md £ 3.6) recorded in 1996 and 1999 by nine digital ...
Castellano, M. +4 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Decoupling transport from economic growth: towards transport sustainability in Europe.
, 2004 This paper reports on a research project that aimed to identify and assess measures which could be used to reduce travel demand while maintaining economic growth and enhancing environmental quality.
Delle Site, P. +5 more
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Random Utility Models of recreation demand are widely used to relate demand and value to the characteristics of recreation sites. Although some kinds of endogeneity problems have been studied in previous literature, no study has addressed the potential ...
Chen, Min
core +2 more sources