Results 41 to 50 of about 2,410,081 (311)
It has long been recognized that the intensity of shaking in the epicentral region in a large earthquake is far from uniform. The common engineering approach has been to regard local site conditions as having paramount influence in the total response prediction problem.
openaire +2 more sources
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
Supporting Survivor‐Centered Care Through Digital Health Integration
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak +15 more
wiley +1 more source
Advance in seismic site response: Usual practices and innovative methods
Amplitudes and frequency content of the seismic ground motion generated by an earthquake and recorded at a specific location depends on the characteristics of the source, the path from the source to the site and the local geologic conditions.
Panzera, Francesco +7 more
core +1 more source
Site-Specific Response Spectra: Guidelines for Engineering Practice
Code response spectrum models, which are used widely in the earthquake-resistant design of buildings, are simple to apply but they do not necessarily represent the real behavior of an earthquake.
Yiwei Hu +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response
This study takes a comprehensive approach to understand the dynamics of the cell-intrinsic response towards virus infection and how viruses actively modulate this. RIG-I recognizes viral dsRNA and activates a cell-autonomous antiviral response.
Sandy S Burkart +12 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The 7.7 and 7.6 magnitude Pazarcık and Elbistan earthquakes that struck Kahramanmaraş on 6 February 2023 caused widespread structural damage across many provinces and are considered rare in seismological terms.
Mahmut Bassurucu +2 more
doaj +1 more source

