Results 61 to 70 of about 2,410,081 (311)

Application of neural networks to obtain the site response in Mexico City

Earth Sciences Research Journal, 2003
<p class="MsoNormal" style="line-height: normal; margin: 0cm 0cm 0pt; mso-layout-grid-align: none;"><span style="font-family: ";Arial";,";sans-serif";; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US">We have implemented a neural ...
Vargas J. Carlos A., Cuenca S. Julio C.
doaj  

Quantifying seismic source, site and path parameters using body wave spectral inversion: a case study from southwestern Saudi Arabia

Frontiers in Earth Science
This study aims to investigate the seismic source characteristics, path attenuation (including geometrical spreading and intrinsic attenuation), and site effects of earthquakes in southwestern Saudi Arabia, with the goal of improving understanding of the
Saleh Qaysi
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Inconsistent growth response to fertilization and thinning of lodgepole pine in the Rocky Mountain Foothills is linked to site index

, 2012
Fertilization of conifers often results in highly variable growth responses across sites which are difficult to predict. The goal of this study was to predict the growth response of lodgepole pine (Pinus contorta var.
Lieffers, V. J., Landhausser, S. M., Pinno, B. D.   +2 more
core   +1 more source

SDM-assist software to design site-directed mutagenesis primers introducing "silent" restriction sites [PDF]

, 2013
BACKGROUND:Over the past decades site-directed mutagenesis (SDM) has become an indispensable tool for biological structure-function studies. In principle, SDM uses modified primer pairs in a PCR reaction to introduce a mutation in a cDNA insert.
Abhijit Karnik, Christopher Grefen, Karnik, Abhijit, Grefen, Christopher, Rucha Karnik, Karnik, Rucha   +5 more
core   +1 more source

Background noise characteristics and site response of strong-motion stations in the Beijing-Tianjin-Hebei region

地震科学进展
The background noise characteristics of 477 strong-motion stations in the Beijing-Tianjin-Hebei region were analyzed using power spectral density, whereas the horizontal-to-vertical spectral ratio (HVSR) was applied to investigate site response ...
Jiaqi Wang
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The direct boundary element method: 2D site effects assessment on laterally varying layered media (methodology)

, 2004
The Direct Boundary Element Method (DBEM) is presented to solve the elastodynamic field equations in 2D, and a complete comprehensive implementation is given. The DBEM is a useful approach to obtain reliable numerical estimates of site effects on seismic
Sánchez-Sesma, Francisco José, Benito, Juan Jose, Sonia Álvarez-Rubio, Alarcón Álvarez, Enrique, Francisco J. Sánchez-Sesma, Enrique Alarcón, Juan José Benito, Álvarez-Rubio, Sonia   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source