Results 161 to 170 of about 9,966,235 (337)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Exploring the Role of Multi-Catalytic Sites in an Amorphous Co–W–B Electrocatalyst for Hydrogen and Oxygen Evolution Reactions [PDF]

open access: hybrid, 2023
Avani Chunduri   +9 more
openalex   +1 more source

Escherichia Species Diversity Across Pristine and Impacted Catchments: Evidence for Avian Sources of Escherichia marmotae in Aotearoa/New Zealand. [PDF]

open access: yesEnviron Microbiol Rep
Cookson AL   +8 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Sr2+ Binding to the Ca2+ Binding Site of the Synaptotagmin 1 C2B Domain Triggers Fast Exocytosis without Stimulating SNARE Interactions [PDF]

open access: bronze, 2003
Ok-Ho Shin   +5 more
openalex   +1 more source

The Impact of Employment Web Sites' Traffic on Unemployment: A Cross Country Comparison

open access: yes, 2014
Although employment web sites have recently become the main source for re- cruitment and selection process, the relation between those sites and unemploy- ment rates is seldom addressed.
Arslan, M. Lutfi, Seker, Sadi Evren
core   +1 more source

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