Results 61 to 70 of about 12,868,149 (415)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Why Youth (Heart) Social Network Sites: The Role of Networked Publics in Teenage Social Life
Social network sites like MySpace and Facebook serve as "networked publics." As with unmediated publics like parks and malls, youth use networked publics to gather, socialize with their peers, and make sense of and help build the culture around them ...
D. Boyd
semanticscholar +1 more source
SNP-sites: rapid efficient extraction of SNPs from multi-FASTA alignments
Rapidly decreasing genome sequencing costs have led to a proportionate increase in the number of samples used in prokaryotic population studies. Extracting single nucleotide polymorphisms (SNPs) from a large whole genome alignment is now a routine task ...
A. Page+6 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Jaworski Véronique. Site classé. In: Revue Juridique de l'Environnement, n°2, 1999. pp. 315-316.
openaire +9 more sources
Atomically dispersed Fe3+ sites catalyze efficient CO2 electroreduction to CO
Three's a charm for iron and CO2 Large-scale electrochemical reduction of CO2 to CO could be a promising first step in sustainable conversion of the greenhouse gas to commodity chemicals.
Jun Gu+4 more
semanticscholar +1 more source
Annotated Records of Species of Pentatomoidea (Hemiptera) Collected at Lights [PDF]
Records of specimens of Pentatomoidea collected at various light sources in Alabama, Arizona, Florida, Georgia, Illinois, Louisiana, and Texas are presented.
McPherson, J. E, Sites, R. W
core +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Site‐directed alkylation and site‐site interactions in bovine seminal ribonuclease [PDF]
Active‐site histidine residues of bovine seminal RNase have been found to react with bromoacetic acid and with 2′(3′)‐O‐bromoacetyluridine (BrAcUrd) at a much faster rate than free histidine. The former reagent reacts preferentially at the pros‐N of His119 the latter is specific for the tele‐N of His12.
Donadio S.+4 more
openaire +4 more sources