Results 71 to 80 of about 9,219,803 (286)
Current trends in the use of residential child care in Scotland [PDF]
, 2006 The survey was planned to examine how local authority residential care units were currently being used and to provide data relating to current issues in the use of residential child care. These issues were identified by Scottish Institute for Residential
Hunter, L., Kendrick, A., Milligan, I.M.
core
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Surveillance, big data and democracy: lessons for Australia from the US and UK [PDF]
, 2014 This article argues that current laws are ill-equipped to deal with the multifaceted threats to individual privacy by governments, corporations and our own need to participate in the information society.
Beatrix van Dissel +2 more
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
InformationConventional spatiotemporal methods take frequentist or density-based approaches to map event clusters over time. While these methods discern hotspots of varying continuity in space and time, their findings overlook locations of routine occurrences where
Yanan Wu, Yalin Yang, May Yuan
doaj +1 more source
The right to legal capacity in Kenya [PDF]
, 2014 The report highlights the voices of people with mental disabilities themselves for the first time, outlining the need for substantial legal and social reform, and provides comprehensive recommendations to bring Kenya in line with international law, and ...
Lewis, Oliver +2 more
core
Causal sites as quantum geometry
, 2004 We propose a structure called a causal site to use as a setting for quantum geometry, replacing the underlying point set. The structure has an interesting categorical form, and a natural "tangent 2-bundle," analogous to the tangent bundle of a smooth ...
Artin M. +5 more
core +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
An application of data mining to fruit and vegetable sample identification using Gas Chromatography-Mass Spectrometry [PDF]
, 2012 One of the uses of Gas Chromatography-Mass Spectrometry (GC-MS) is in the detection of pesticide residues in fruit and vegetables. In a high throughput laboratory there is the potential for sample swaps or mislabelling, as once a sample has been pre ...
Fletcher, Dale +2 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source