Results 51 to 60 of about 65,671 (281)

First Discovery of Beta-Sitosterol as a Novel Antiviral Agent against White Spot Syndrome Virus

International Journal of Molecular Sciences, 2022
The outbreak of white spot syndrome (WSS) is a looming challenge, due to dramatic losses to the crustacean aquaculture industry. However, at present, there are no prophylactic or therapeutic means to control this infectious viral disease.
Cheng Chen, Jing Shen, Chang-Shuai Liang, Zhong-Chen Sun, Hai-Feng Jiang   +4 more
semanticscholar   +1 more source

Chromosomal location of a gene that controls sterol esterification in Triticum aestivum L. [PDF]

, 1974
A previously described D genome locus (Pln) that controls sterol esterification in the wheat kernel has been assigned to the short arm of chromosome 7 D by comparison of the steryl ester phenotype of euploid kernels of Triticum aestivum variety Chinese ...
Bennett, Bondjers, Bush, Carbonero, Dupéron, Dupéron, F. Garcia-Olmedo, García-Faure, García-Olmedo, García-Olmedo, Gilles, Grunwald, Grunwald, Hartman, J.V. Torres, Kemp, Méance, Skarsaune   +17 more
core   +2 more sources

β-sitosterol inhibits trimethylamine production by regulating the gut microbiota and attenuates atherosclerosis in ApoE–/– mice

Frontiers in Cardiovascular Medicine, 2022
The intestinal microbial metabolite trimethylamine (TMA), which is activated by flavin monooxygenase (FMO) to produce trimethylamine-N-oxide (TMAO), has been implicated in the pathogenesis of atherosclerosis (AS), leading to the development of ...
Weiping Wu, Wugao Liu, Huafu Wang, Wei Wang, W. Chu, Jing Jin   +5 more
semanticscholar   +1 more source

β-Sitosterol Inhibits The Proliferation of Endometrial Cells via Regulating Smad7-Mediated TGF-β/Smads Signaling Pathway [PDF]

Cell Journal, 2023
Objective: To investigate the effect of β-sitosterol on endometrial cells to understand the underlying mechanism.Materials and Methods: This is a laboratory-based experimental study conducted on animals and cells.
Yi Wen, Lili Pang, Lingxiu Fan, Yihan Zhou, Ruonan Li, Tingting Zhao, Manli Zhang   +6 more
doaj   +1 more source

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]

, 2016
Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph, Burdman, Saul, Cárdenas, Pablo D, Dewangan, Veena, Giri, Ashok P, Goossens, Alain, Malitsky, Sergey, Meir, Sagit, Pollier, Jacob, Rogachev, Ilana, Sonawane, Prashant D, Tal, Lior, Vanden Bossche, Robin, Weithorn, Efrat   +13 more
core   +1 more source

Exploring the possible mechanism involved in the anti-nociceptive effect of β-sitosterol: modulation of oxidative stress, nitric oxide and IL-6

InflammoPharmacology, 2022
Β-sitosterol is a phytosterol, documented to possess various activities including protection against inflammation, diabetes and Alzheimer’s disease.
Kiranjot Kaur, L. Singh, Anudeep Kaur, R. Bhatti   +3 more
semanticscholar   +1 more source

The relationships of cholesterol metabolism and plasma plant sterols with the severity of coronary artery disease1s⃞

Journal of Lipid Research, 2009
Changes in the balance of cholesterol absorption and synthesis and moderately elevated plasma plant sterols have been suggested to be atherogenic. Measuring cholestanol, lathosterol, campesterol, and sitosterol, we investigated the relationships of ...
Guenther Silbernagel, Guenter Fauler, Wilfried Renner, Eva M. Landl, Michael M. Hoffmann, Bernhard R. Winkelmann, Bernhard O. Boehm, Winfried März   +7 more
doaj   +1 more source

β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice

Cell Reports Medicine, 2021
Summary Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage.
N. Panayotis, P. A. Freund, Letizia Marvaldi, Tali Shalit, A. Brandis, Tevie Mehlman, M. Tsoory, M. Fainzilber   +7 more
semanticscholar   +1 more source

Stinging Nettle (Urtica dioica) Roots: The Power Underground—A Review

Plants
Stinging nettle (Urtica dioica) is an herbaceous perennial plant native to Eurasia, wildly distributed throughout the temperate parts of the world. Although generally considered as a weed due to its fast growth and invasive capacity, stinging nettle is ...
Françoise Martz, Santeri Kankaanpää
doaj   +1 more source

ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile

Journal of Lipid Research, 2005
The major pathway for the removal of cholesterol from the body is via secretion into the bile. Three members of the ATP binding cassette (ABC) family, ABCG5 (G5), ABCG8 (G8), and ABCB4 (MDR2), are required for the efficient biliary export of sterols ...
Silvia Langheim, Liqing Yu, Klaus von Bergmann, Dieter Lütjohann, Fang Xu, Helen H. Hobbs, Jonathan C. Cohen   +6 more
doaj   +1 more source