Results 61 to 70 of about 19,281 (197)

In Vitro Antidiabetic Evaluation and Phytochemical Characterization of Sapindus mukorossi Fruit Pericarp Extract

Applied Research, Volume 5, Issue 4, August 2026.
Sapindus mukorossi fruit pericarp is a promising source of polar polyphenols and amphiphilic saponins, with the 70% ethanol extract showing the richest phytochemical profile and strongest α‐amylase inhibition. Its solvent‐dependent bioactive composition suggests potential application in managing postprandial hyperglycemia by modulating dietary starch ...
Keisham Subharani Devi, Leishangthem Jetlee Singh, Kongbrailatpam Gayatri Sharma, Thokchom Prasanta Singh   +3 more
wiley   +1 more source

Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption

Journal of Lipid Research, 2002
Heredity of cholesterol absorption and synthesis was studied in siblings of hypercholesterolemic probands with low and high serum cholestanol to cholesterol ratio (assumed to indicate low and high absorption of cholesterol, respectively).
Helena Gylling, Tatu A. Miettinen
doaj   +1 more source

Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo, Miriam Arlette López‐Pérez, Ana Karen Villagómez‐Guzmán, Edgar Antonio Estrella‐Parra, Nallely Álvarez‐Santos, Israel Valencia‐Quiroz, Julieta Orozco‐Martínez, Ma. Edith López‐Villafranco, Silvia Aguilar‐Rodríguez, Carlos Leonardo Céspedes‐Acuña, Juio Alarcón‐Enos, Ana María García‐Bores   +11 more
wiley   +1 more source

A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome

Journal of Lipid Research
Disease-specific sterols accumulate in the blood of patients with several rare lipid disorders. Biochemical measurement of these sterols is important for correct diagnosis and sometimes monitoring of treatment.
Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl   +8 more
doaj   +1 more source

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

Journal of Lipid Research, 2004
Type 2 diabetes has been associated with high synthesis and low absorption of cholesterol independent of weight, indicating that insulin resistance may be a link between glucose and cholesterol metabolism.
Jussi Pihlajamäki, Helena Gylling, Tatu A. Miettinen, Markku Laakso   +3 more
doaj   +1 more source

Bioaccessibility of Phytochemicals, Amino Acids, Antioxidant Capacity, and Enzyme Inhibitory Activities of Hawthorn (Crataegus spp.) Fruits Following INFOGEST Simulated Gastrointestinal Digestion

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Comprehensive compositional and functional characterization of three Crataegus species demonstrated that simulated gastrointestinal digestion substantially altered the bioaccessibility of phenolic compounds and associated biological activities. The pronounced interspecific variation observed highlights the importance of species selection for the ...
Kubra Feyza Erol, Gozde Kutlu, Hatice Bekiroglu, Osman Sagdıc, Fatih Tornuk   +4 more
wiley   +1 more source

Isolation and identification of secondary metabolites from Artemisia sodiroi Hieron

ACI Avances en Ciencias e Ingenierías, 2011
Artemisia sodiroi Hieron (Asteraceae), commonly known as “Ajenjo”, is used in traditional medicine in Southern Ecuador for the treatment of inflammations, stomachaches, hepatic pains, fever, kidney problems, headaches, cough and by women to ...
Talía Briceño, César M. Compadre, Paola Ordóñez, Omar Malagón   +3 more
doaj   +1 more source

Mechanisms of Lycium barbarum Treatment in Sepsis‐Induced Myocardial Injury: A Network Pharmacology and Experimental Validation Study

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The chemical characterization of the LB extract confirmed the presence of polysaccharides and specific small‐molecule constituents (e.g., rutin, isoquercitrin). Network pharmacology analysis predicted that the bioactive components of LB were able to interact with core targets such as TP53, AKT1, and JUN, and molecular docking simulations suggested ...
Ruxin Liu, Chunxia Ma, Yujiao Tang, Xue Bai, Liting Yang, Yi Hu, Zesu Niu, Weiliang Xue, Ling Zhang, Mengfei Chen   +9 more
wiley   +1 more source

Integrative GC–MS, FT‐IR, and Molecular Docking Analysis of Drimycarpus racemosus (Roxb.) Hook.f ex Marchand: In Vivo Analgesic and Antidiabetic Potential

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
GC–MS profiling of D. racemosus identified bioactive phytochemicals with promising molecular interactions through docking analysis. The methanolic extract demonstrated significant antinociceptive activity against acetic acid‐ and formalin‐induced pain and exhibited antidiabetic effects in streptozotocin‐induced diabetic Swiss albino mice, supporting ...
Md Sajib Ali, Md. Rakibul Islam, M. A. Rafi, Sanjana Haque Esha, Md. Mehedi Hasan, Payar Hossain, Abdullah Ripon, Nilufar Sultana   +7 more
wiley   +1 more source

Comparison of the effects of maximal dose atorvastatin and rosuvastatin therapy on cholesterol synthesis and absorption markers*[S]

Journal of Lipid Research, 2009
We measured plasma markers of cholesterol synthesis (lathosterol) and absorption (campesterol, sitosterol, and cholestanol) in order to compare the effects of maximal doses of rosuvastatin with atorvastatin and investigate the basis for the significant ...
Thomas M. van Himbergen, Nirupa R. Matthan, Nancy A. Resteghini, Seiko Otokozawa, Masumi Ai, Evan A. Stein, Peter H. Jones, Ernst J. Schaefer   +7 more
doaj   +1 more source