Results 41 to 50 of about 756 (157)

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

From pollen provision to pollinator: Species‐specific sterol assimilation by wild bees in urban landscapes

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven landscape change, particularly urbanization, is reshaping pollinator communities, yet the functional traits that mediate species persistence remain poorly understood. Dietary specialization is commonly used to predict species vulnerability.
Yan Yang, Joan Casanelles‐Abella, Marco Moretti, Consuelo M. De Moraes, Mark C. Mescher, Pengjuan Zu   +5 more
wiley   +1 more source

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Polar Lipid and Fatty Acid Profiles of Oat Groats Substantially Influenced by Field Management: A Comparison of Cultivars, Sowing Times and Fertilizer Composition

Plant, Cell &Environment, EarlyView.
ABSTRACT The polar lipids in oat grains are crucial due to their biological functions, nutritional quality, potential use in food flavour and processing, the protection they provide against biotic and abiotic stresses, and their ability to act as cellular signalling molecules.
Syed Rehmat Ullah Shah, Lena Engström, Carl Grey, Anders Jonsson, Johanna Wetterlind, Cecilia Tullberg   +5 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Fats, Fire and Bronze Age Funerary Rites: Organic Residue Analysis of Wide Horizontal Rim Vessels From Burial Contexts in Northwest Portugal

Archaeometry, Volume 68, Issue 3, Page 298-310, June 2026.
ABSTRACT This study presents the first GC‐MS–based analyses of wide horizontal rim vessels with well‐defined funerary contexts, from Middle Bronze Age Portugal (Quinta do Amorim 2 and Pego). Organic residues from two vessels revealed ruminant fats and plant oils, alongside molecular markers of heat exposure.
João Vinícius Back, César Oliveira, Ana M. S. Bettencourt, Hugo Aluai Sampaio, Luciano Vilas Boas, Luís Gonçalves   +5 more
wiley   +1 more source

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, Volume 299, Issue 6, Page 711-725, June 2026.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source