Results 171 to 180 of about 279,956 (268)

Droplets sitting on thin elastic sheets: a study with the boundary element method. [PDF]

Eur Phys J E Soft Matter
Sultan S, Grawitter J, Antunes GC, Stark H.   +3 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The association between physical activity and adolescent idiopathic scoliosis: improper sitting posture as a mediator. [PDF]

Front Pediatr
Wang L, Ge P, Wang H.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Factors associated with musculoskeletal pain in the spinal column of children and adolescents: a cross-sectional study with network analysis. [PDF]

Rev Paul Pediatr
Gomes MVP, Belém RSM, Pantoja AVG, Costa BDS, Jardim NYV, Crisp AH, Magalhães MO.   +6 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity. [PDF]

J Frailty Aging
de Matos DG, Aidar FJ, Nunes-Silva A, Peringod G, Giambusso V, Romero-Ortuno R, Duhamel TA, Villar R.   +7 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Sitting [PDF]

San Antonio Review, 2019
openaire   +1 more source

Body Posture-Related Differences in Pain Perception and Their Mediation by Cardiovascular Factors. [PDF]

Psychophysiology
Reyes Del Paso GA, Santiago D, Moreno B, Montoro CI, Duschek S, Davydov DM.   +5 more
europepmc   +1 more source