Results 61 to 70 of about 279,956 (268)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Cerebral hemodynamic response to upright position in acute ischemic stroke

Frontiers in Neurology
IntroductionConcerns exist that a potential mechanism for harm from upright activity (sitting, standing, and walking) early after an acute ischaemic stroke could be the reduction of cerebral perfusion during this critical phase.
Lilian B. Carvalho, Tina Kaffenberger, Brian Chambers, Karen Borschmann, Karen Borschmann, Christopher Levi, Leonid Churilov, Vincent Thijs, Vincent Thijs, Julie Bernhardt   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Evaluation of Office Chair Comfort

Drvna Industrija, 2016
The studies of office chair constructions have identified differences in perception of comfort provided by different types of seats. Four seat constructions and the comfort provided to the users were compared by means of subjective indicators.
Zoran Vlaović, Danijela Domljan, Ivica Župčić, Ivica Grbac   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Comparison of sedentary time, number of steps and sit-to-stand-transitions of desk-based workers in different office environments including working from home: analysis of quantitative accelerometer data from the cross-sectional part of the SITFLEX Study

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: Sedentary behavior is associated with diseases (eg, cardiovascular, diabetes type 2). We aimed to describe the sitting and moving behavior of desk-based hybrid employees of a large company in Germany working in either a traditional open plan ...
Martha Sauter, Eva Backé, Carina Pfab, Michaela Prigge, Claudia Brendler, Falk Liebers, Peter von Löwis, Andrea Pfeiffer, Falko Papenfuss, Janice Hegewald   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Biological, psychological, social and environmental correlates of health enhancing physical activity in adults in Ostrava region using the formal concept analysis

Tělesná Kultura, 2011
BACKGROUND: Optimal physical activity (PA) is next to balanced healthy diet and medical care one of the key determinants of prevention of overweight and obesity.
Igor Fojtík, Sigmund Erik, Oldřich Mičan, Dagmar Sigmundová   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source