Results 71 to 80 of about 286,272 (317)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Biological, psychological, social and environmental correlates of health enhancing physical activity in adults in Ostrava region using the formal concept analysis

Tělesná Kultura, 2011
BACKGROUND: Optimal physical activity (PA) is next to balanced healthy diet and medical care one of the key determinants of prevention of overweight and obesity.
Igor Fojtík, Sigmund Erik, Oldřich Mičan, Dagmar Sigmundová   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Post Utme Form for Tansian University,2022/2023,(Admission Form) Undergraduate is Out Call ADMIN "0806-591-2405 ☎ Dr Mrs. GRACE General Requirements The minimum entry requirements for admission into Covenant University are credit level passes in five (5) subjects at the SSCE/GCE O'Level/NECO or its equivalent, obtained at not more than two (2) sittings. The subjects passed must include English Language and Mathematics.

, 2022
08065912405
openalex   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

UPDATES!!! Redeemer's University 2022/2023 Pre-Degree/ Jupeb/REMEDIAL Admission Form ☎" 0706_5086_538, ☎+23470-6508-6538 Prof Mrs ANITA the Degree Programme is 5 credits including English Language, Mathematics and any three other relevant subjects at the WASC/NECO/NABTEB Examinations or their equivalent (at not more than 2 sittings

, 2022
javvy
openalex   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Christopher University Admission Form, 2022/2023 Post gradutate/Post UTME FORM is Out ☎ 07066280862 ☎ 07066280862,CHANGE OF COURSE,JUPEBFORM [07066280862) Candidates Nigeria must posses the Senior Secondary School Certificate or its equivalent with five credits to include English Language and either Physics, Chemistry, Biology/Health Science at not more than 2 sittings.

, 2022
james b
openalex   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Exploring Associations Between Device-Based Occupational Sedentary Behavior and Need for Recovery in White Collar Workers: A Compositional Data-Analysis

International Journal of Public Health
ObjectivesWhite collar workers spend an increasing amount of time in occupational sedentary behavior (OSB) and are thereby at risk for adverse health outcomes.
Denise J. M. Smit, Denise J. M. Smit, Laura J. G. C. Burgers, Sandra H. van Oostrom, Henri Vähä-Ypyä, Pauliina Husu, Simone J. J. M. Verswijveren, Karin I. Proper, Karin I. Proper   +8 more
doaj   +1 more source