Results 91 to 100 of about 407,599 (315)

Ergonomic Evaluation of Relationship between Electromyographic Activity in Selected Trunk Muscles and Back Discomfort While Working with a Laptop in a Sitting Position

open access: yesبهداشت و ایمنی کار, 2021
Introduction: Low back pain is one of the most common musculoskeletal disorders leading to disability around the world. Several studies have suggested that prolonged computer/ laptop work contributes to the development of low back pain and discomfort ...
Mohammad Yadegaripour   +3 more
doaj  

Cross-sectional associations between sitting time and several aspects of mental health in Belgian adults

open access: yes, 2015
Background: Sedentary behavior (including sitting) is negatively associated with physical health, independent from physical activity (PA). Knowledge on the associations with mental health is less elaborated.
De Bourdeaudhuij, Ilse   +3 more
core   +1 more source

Validation of a novel, objective measure of occupational sitting [PDF]

open access: yes, 2012
Validation of a Novel, Objective Measure of Occupational Sitting: Gemma C. RYDE, et al. St Lucia Campus, School of Human Movement Studies, The University of Queensland, Australia-Objective: To test the validity of a sitting pad (SP) to measure desk based
Gilson, Nicholas D   +15 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Associations of objectively measured sitting and standing with low-back pain intensity: a 6-month follow-up of construction and healthcare workers

open access: yesScandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: This study aimed to determine the associations between objectively measured sitting and standing duration and intensity of low-back pain (LBP) among Norwegian construction and healthcare workers.
Lars-Kristian Lunde   +3 more
doaj   +1 more source

The effectiveness of a web-based computer-tailored intervention on workplace sitting : a randomized controlled trial

open access: yes, 2016
BACKGROUND: Effective interventions to influence workplace sitting are needed, as office-based workers demonstrate high levels of continued sitting, and sitting too much is associated with adverse health effects.
De Cocker, K   +7 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Sitting time In adults 65 years and over: Behaviour, knowledge, and intentions to change [PDF]

open access: yes, 2018
Alley, SJ ORCiD: 0000-0001-9666-5071; Schoeppe, S ORCiD: 0000-0003-1937-876X; Vandelanotte, CL ORCiD: 0000-0002-4445-8094This study examined sitting time, knowledge and intentions to change sitting time in older adults.
De Cocker, Katrien   +30 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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