Results 91 to 100 of about 407,599 (315)
Introduction: Low back pain is one of the most common musculoskeletal disorders leading to disability around the world. Several studies have suggested that prolonged computer/ laptop work contributes to the development of low back pain and discomfort ...
Mohammad Yadegaripour +3 more
doaj
Background: Sedentary behavior (including sitting) is negatively associated with physical health, independent from physical activity (PA). Knowledge on the associations with mental health is less elaborated.
De Bourdeaudhuij, Ilse +3 more
core +1 more source
Validation of a novel, objective measure of occupational sitting [PDF]
Validation of a Novel, Objective Measure of Occupational Sitting: Gemma C. RYDE, et al. St Lucia Campus, School of Human Movement Studies, The University of Queensland, Australia-Objective: To test the validity of a sitting pad (SP) to measure desk based
Gilson, Nicholas D +15 more
core +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
OBJECTIVES: This study aimed to determine the associations between objectively measured sitting and standing duration and intensity of low-back pain (LBP) among Norwegian construction and healthcare workers.
Lars-Kristian Lunde +3 more
doaj +1 more source
BACKGROUND: Effective interventions to influence workplace sitting are needed, as office-based workers demonstrate high levels of continued sitting, and sitting too much is associated with adverse health effects.
De Cocker, K +7 more
core +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Sitting time In adults 65 years and over: Behaviour, knowledge, and intentions to change [PDF]
Alley, SJ ORCiD: 0000-0001-9666-5071; Schoeppe, S ORCiD: 0000-0003-1937-876X; Vandelanotte, CL ORCiD: 0000-0002-4445-8094This study examined sitting time, knowledge and intentions to change sitting time in older adults.
De Cocker, Katrien +30 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

