Results 101 to 110 of about 279,956 (268)

Variability of selected indicators of physical activity in a randomized sample of the Czech population between the years 2003–2006: Results from the short and long self administered format of the IPAQ questionnaire [Variabilita vybraných indikátorů pohybové aktivity u randomizovaných souborů české populace v letech 2003–2006: Výsledky z krátké a dlouhé administrativní verze IPAQ dotazníku]

open access: yesActa Universitatis Palackianae Olomucensis. Gymnica, 2009
BACKGROUND: The effort to gain worldwide data on the levels of physical activity (PA) of different populations, which would be comparable, led to the creation and standardization of the International Physical Activity Questionnaire (IPAQ). OBJECTIVE: The
Erik Sigmund   +5 more
doaj  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Bone mineral density and accelerometer-determined habitual physical activity and inactivity in postmenopausal women [Kostní denzita a habituální pohybová aktivita a inaktivita u postmenopauzálních žen]

open access: yesActa Universitatis Palackianae Olomucensis. Gymnica, 2011
BACKGROUND: In postmenopausal women, physical activity appears to be important in preventing loss of bone mineral density (BMD) and osteoporosis and thus contributes to the reduction of fracture risk.
Ondřej Kapuš   +2 more
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Sitting on the fence [PDF]

open access: yesNature Clinical Practice Gastroenterology & Hepatology, 2008
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Early sitting within 72 hours in the intensive care unit and post-intensive care outcomes: a multicenter cohort study. [PDF]

open access: yesAnn Intensive Care
Watanabe S   +9 more
europepmc   +1 more source

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