Results 91 to 100 of about 15,435,920 (254)

Differential cross-sectional associations of work- and leisure-time sitting, with cardiorespiratory and muscular fitness among working adults

Scandinavian Journal of Work, Environment & Health, 2014
OBJECTIVES: Sedentary behavior is increasingly recognized as a risk factor for cardiovascular and metabolic morbidity and mortality. Recent studies suggest that sitting during work and leisure time may affect markers of cardiometabolic health ...
Madina Saidj, Torben Jørgensen, Rikke K Jacobsen, Allan Linneberg, Mette Aadahl   +4 more
doaj   +1 more source

Office workers' objectively assessed total and prolonged sitting time: Individual-level correlates and worksite variations

Preventive Medicine Reports, 2016
Sedentary behavior is highly prevalent in office-based workplaces; however, few studies have assessed the attributes associated with this health risk factor in the workplace setting.
Nyssa T. Hadgraft, Genevieve N. Healy, Neville Owen, Elisabeth A.H. Winkler, Brigid M. Lynch, Parneet Sethi, Elizabeth G. Eakin, Marj Moodie, Anthony D. LaMontagne, Glen Wiesner, Lisa Willenberg, David W. Dunstan   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Cumulative sitting time as discriminator of overweight, obesity, abdominal obesity and lipid disorders in nursing university

Revista Brasileira de Cineantropometria e Desempenho Humano, 2017
There is evidence demonstrating that prolonged sitting time is relevant risk factors for metabolic and cardiovascular disorders. The aim of this study was to identify the discriminatory power and propose cumulative sitting time cutoff points for ...
Fernanda Carneiro Mussi, Francisco Jose Gondim Pitanga, Cláudia Geovana da Silva Pires   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Regulate your Sitting Time (RESIT) intervention for reducing sitting time in individuals with type 2 diabetes: findings from a randomised-controlled feasibility trial. [PDF]

Diabetol Metab Syndr
Background Reducing and breaking up sitting is recommended for optimal management of Type 2 diabetes mellitus (T2DM). Yet, there is limited evidence of interventions targeting these outcomes in individuals with this condition.
Brierley ML, Chater AM, Edwardson CL, Castle EM, Hunt ER, Biddle SJ, Sisodia R, Bailey DP.   +7 more
europepmc   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Breaking up sitting time after stroke (BUST-stroke)

, 2018
Objectives: People with stroke sit for long periods each day, which may compromise blood glucose control and increase risk of recurrent stroke. Studies in other populations have found regular activity breaks have a significant immediate (within-day ...
Bernhardt, Julie, Crowfoot, Gary, Walker, F. Rohan, Dunn, Ashlee, Palazzi, Kerrin, Callister, Robin, Mackie, Paul, Dunstan, David W., Spratt, Neil J., Janssen, Heidi, Oldmeadow, Christopher, English, Coralie, Ong, Lin K., Patterson, Amanda J.   +13 more
core   +1 more source