Results 101 to 110 of about 14,817,059 (300)

Associations of Leisure-Time Sitting in Cars With Neighborhood Walkability

Journal of Physical Activity and Health, 2014
Background:Too much sitting, including time spent sitting in cars, is associated with poor health outcomes. Identifying the built-environment attributes that may reduce vehicular sitting time can inform future initiatives linking the public health, urban design, and transportation sectors.Methods:Data collected in 2003–2004 from adult residents (n ...
Koohsari, Mohammad Javad, Sugiyama, Takemi, Kaczynski, Andrew T., Owen, Neville   +3 more
openaire   +4 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Low back pain and sickness absence among sedentary workers: the influence of lumbar sagittal movement characteristics and psychosocial factors [PDF]

Introduction: Low back pain remains a burden for society, since it can lead to sickness absence and work disability. Physical occupational risk factors can contribute to the development of back pain, yet little is known about any risks in sedentary ...
Bell, Jamie
core   +4 more sources

Change in Physical Activity and Sitting Time After Myocardial Infarction and Mortality Among Postmenopausal Women in the Women's Health Initiative‐Observational Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background How physical activity (PA) and sitting time may change after first myocardial infarction (MI) and the association with mortality in postmenopausal women is unknown.
Anna M. Gorczyca, Charles B. Eaton, Michael J. LaMonte, JoAnn E. Manson, Jeanne D. Johnston, Aurelian Bidulescu, Molly E. Waring, Todd Manini, Lisa W. Martin, Marcia L. Stefanick, Ka He, Andrea K. Chomistek   +11 more
doaj   +1 more source

Worldwide surveillance of self-reported sitting time: a scoping review

International Journal of Behavioral Nutrition and Physical Activity, 2020
Background Prolonged sitting time is a risk factor for chronic disease, yet recent global surveillance is not well described. The aims were to clarify: (i) the countries that have collected country-level data on self-reported sitting time; (ii) the ...
M. Mclaughlin, A. J. Atkin, L. Starr, A. Hall, L. Wolfenden, R. Sutherland, J. Wiggers, A. Ramirez, P. Hallal, M. Pratt, B. M. Lynch, K. Wijndaele, on behalf of the Sedentary Behaviour Council Global Monitoring Initiative Working Group   +12 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Letter from Mrs. John Sitting Crow to Congressman Burdick Regarding Fort Berthold Claims, February 25, 1954

, 1954
This letter, dated February 25 1954, from Mrs. John Sitting Crow of New Town North Dakota to United States (US) Representative Usher Burdick refers to the Three Affiliated Tribes of the Fort Berthold Reservation\u27s claims before the US Court of Claims.
Sitting Crow,
core   +1 more source

Comparison of Postures According to Sitting Time with the Leg Crossed

Journal of Physical Therapy Science, 2014
[Purpose] The purpose of this study was to identify postural changes in adults who have adopted the habit of sitting with their legs crossed. [Subjects and Methods] The subjects were 232 adults in their 20s and 30s (84 males and 148 females). They were divided into 0-, 1-, 2-, and 3-hour or more groups by observing how much time per day they sat with ...
Park, Yongnam, Bae, Youngsook
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source