HIV sequence diversity and the propensity of eliciting immunodominant responses targeting inessential variable regions are hurdles in the development of an effective AIDS vaccine.
Xintao Hu +9 more
doaj +1 more source
Schlieren Image Velocimetry and colorimetry for a burning candle and its thermal plume [PDF]
This article explores the feasibility of generating velocity maps for a flame and its plume from a burning candle using Schlieren Image Velocimetry (SIV). Currently, SIV is predominantly employed in the literature to track highly turbulent flows by using
Raluca Andreea ROSU
doaj +1 more source
Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers. [PDF]
Lymphoid tissue immunopathology is a characteristic feature of chronic HIV/SIV infection in AIDS-susceptible species, but is absent in SIV-infected natural hosts.
Amanda J Martinot +9 more
doaj +1 more source
Brain viral reservoir seeding and neurological metabolic dysregulation in early-life immunodeficiency virus infection. [PDF]
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Ma L +12 more
europepmc +2 more sources
Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication
Background An understanding of host cell factors that affect viral replication contributes to elucidation of the mechanism for determination of viral tropism.
Takeuchi Hiroaki +5 more
doaj +1 more source
The simian immunodeficiency virus (SIV) precursor polypeptide Pr55Gag drives viral assembly and facilitates specific recognition and packaging of the SIV genomic RNA (gRNA) into viral particles.
Vineeta N. Pillai +6 more
doaj +1 more source
Production of replication-defective SIV particles by rRRV-SIV-nfl.
A) Early passage rhesus fibroblast (RF) cells were grown in 6-well culture plates and subsequently infected with 3.5x109 genome copies of the indicated recombinant SIV-nfl. The RF cell culture supernatants were collected at the indicated time points post
Gregory M. Hendricks (5410901) +8 more
core +1 more source
A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products. [PDF]
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus ...
Young C Shin +8 more
doaj +1 more source
SIV-infected cells localize around the portal triads.
A) RNAscope in situ hybridization was used to detect SIV RNA-positive cells in the liver. Images were captured from whole tissue scans at 5x magnification (images outlined in red, scale bar = 500 um) and depict SIV-infected cells around the portal triads.
Andrew D. Miller (328799) +16 more
core +1 more source
Siv Jensen: “The EEA agreement has served Norway well, but it’s not a free ride” [PDF]
Norway, as one of the largest oil and gas exporters in the world, has had to cope with a substantial drop in the price of oil since 2014. The country is also frequently cited in the context of the UK’s upcoming referendum as a potential model for Britain
Jensen, Siv
core +5 more sources

