Results 91 to 100 of about 672,828 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A six-phase series-connected two-motor drive with decoupled dynamic control supplied by a three-level six-phase inverter

open access: yesRevue des Énergies Renouvelables, 2018
This paper presents independent vector control of six-phase two-motor drive machine series-connected fed by a three-level six-phase inverter. Via appropriate phase transposition during the series connection of the stator windings, the fully decoupled ...
T. Bessaad   +3 more
doaj  

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]

open access: yes, 2018
The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria   +11 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Effects of hemodialysis therapy on sit-to-walk characteristics in end stage renal disease patients [PDF]

open access: yes, 2012
Patients with end stage renal diseases (ESRD) undergoing hemodialysis (HD) have high morbidity and mortality due to multiple causes; one of which is dramatically higher fall rates than the general population.
Abdel-Rahman, Emaad   +3 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Controller for computer control of brushless dc motors [PDF]

open access: yes, 1981
A motor speed and torque controller for brushless d.c. motors provides an unusually smooth torque control arrangement. The controller provides a means for controlling a current waveform in each winding of a brushless dc motor by synchronization of an ...
Hieda, L. S.
core   +1 more source

Maximum power operation of interacting molecular motors

open access: yes, 2013
We study the mechanical and thermodynamic properties of different traffic models for kinesin which are relevant in biological and experimental contexts.
Golubeva, Natalia, Imparato, Alberto
core   +1 more source

Performance estimation of interior permanent-magnet brushless motors using the voltage-driven flux-MMF diagram [PDF]

open access: yes, 2006
The flux-magnetomotive force (flux-MMF) diagram, or "energy conversion loop," is a powerful tool for computing the parameters of saturated interior permanent-magnet brushless motors, especially when the assumptions underlying classical dq theory are not ...
Cossar, C.   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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