Results 71 to 80 of about 672,828 (298)

Time-Restricted Feeding Improves Circadian Dysfunction as well as Motor Symptoms in the Q175 Mouse Model of Huntington's Disease. [PDF]

, 2018
Huntington's disease (HD) patients suffer from a progressive neurodegeneration that results in cognitive, psychiatric, cardiovascular, and motor dysfunction.
Colwell, Christopher S, Cutler, Tamara, Howland, David, Loh, Dawn H, Wang, Huei-Bin, Whittaker, Daniel S   +5 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analysis and design of 18-slot/10-pole six-phase fault-tolerant permanent magnet synchronous motor for electric vehicles

The Journal of Engineering, 2020
This study analyses a double Y shaft 30° winding for six-phase fault-tolerant permanent magnet synchronous motors and introduces a novel modular 18-slot stator topology used in high-performance electric vehicles with unequal teeth width and unequal slot ...
Zhong An Yu, Junming Zhang, Jianwei Liang, Jian Lu   +3 more
doaj   +1 more source

Performance analysis of dual stator six‐phase embedded‐pole permanent magnet synchronous motor for electric vehicle application

IET Electrical Systems in Transportation, 2023
The motive of this study is to analyse the characteristics of a novel dual‐stator embedded‐pole six‐phase permanent magnet synchronous motor for the application of electric vehicles.
Raja Ram Kumar, Priyanka Devi, Chandan Chetri, Ankita Kumari, Papu Moni Saikia, Ram Khelawan Saket, Kundan Kumar, Baseem Khan   +7 more
doaj   +1 more source

Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study [PDF]

, 2009
Objective: To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after de-training or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury (SCI ...
Coupaud, S., Eser, P., Frotzler, A., Hunt, K.J., Kakebeeke, T.H., Perret, C.   +5 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Sensorless flux-weakening control of permanent-magnet brushless machines using third harmonic back EMF [PDF]

, 2004
The sensorless control of brushless machines by detecting the third harmonic back electromotive force is a relatively simple and potentially low-cost technique.
Howe, D., Shen, J.X., Zhu, Z.Q.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Sensorless Direct Torque Control of the Six-Phase Induction Motor by Fast Reduced Order Extended Kalman Filter

Complexity, 2020
In this paper, a simple extended Kalman Filter (EKF) controller for direct torque control (DTC) of a six-phase induction machine in all speed ranges is proposed.
Asghar Taheri, Hai-Peng Ren, Chun-Huan Song   +2 more
doaj   +1 more source

Synchronization of Speech and Gesture : Evidence for Interaction in Action [PDF]

, 2014
Peer ...
Chu, Mingyuan, Hagoort, Peter
core   +3 more sources