Results 51 to 60 of about 3,616,780 (267)
Barriers of six sigma in healthcare organizations [PDF]
Management Science Letters, 2018 Six Sigma approach is based on decreasing defects and variations in the products and processes, and it provides important benefits to healthcare organizations.
Serkan Deniz , Mesut Çimen
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Teknika, 2020 PT. XYZ merupakan industri manufaktur dalam bidang pembuatan dunnage. Dalam proses produksinya, masih ditemukan pemborosan yang mengakibatkan cacatan pada produk dunnage.
Asep Ridwan, Faula Arina, Ardi Permana
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Determining the essential characetristics of Six Sigma Black Belts [PDF]
, 2007 A Six Sigma Black Belt (SSBB) plays the role of a full-time team leader responsible for implementing process improvement projects using the Six Sigma methodology (Define-Measure-Analyse-Improve-Control) within the business to drive up customer ...
Antony, Jiju
core +4 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
ANALISIS PENGENDALIAN KUALITAS PROSES PENGANTONGAN SEMEN
Journal of Engineering and Management in Industrial System, 2016 PT. Semen Indonesia (Persero), Tbk is a leading cement producer. So the need to apply a good quality control system on all of its products and service to customers throughout the process.
Dwi Hadi Sulistyarini +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source