Results 61 to 70 of about 3,616,780 (267)
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
A theoretical framework for exploring the effect of the Six Sigma management activities on corporate competitiveness [PDF]
, 2011 Six Sigma has long been used as an effective way to restructure a company’s management process. While there are abundant case study literatures on Six Sigma, a theoretical framework that can logically advance the previous work into a higher level is ...
Lee, Kun-Chang, Choi, Bong, Li, Honglei
core
Spektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik IndustriIn pharmaceutical manufacturing, inefficiencies such as waiting times, excessive material usage, and packaging defects can significantly impact productivity and quality.
Rindi Kusumawardani +1 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Six Sigma Driven Enterprise Model Transformation
International Journal of Engineering Business Management, 2009 Enterprise architecture methods provide a structured system to understand enterprise activities. However, existing enterprise modelling methodologies take static views of the enterprise and do not naturally lead to a path of improvement during enterprise
Raymond Vella +2 more
doaj +2 more sources
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Six Sigma vs. Design for Six Sigma: selection of the requisite Six Sigma approach using multi-criteria decision analysis: innovation report [PDF]
The literature suggests that organisations which have adopted Six Sigma have realised that upon achieving a Five Sigma level the only way to surpass this is to redesign the process(es) by means of Design for Six Sigma (DFSS). For others, the selection of
Bañuelas, Ricardo
core
In–Vitro Antifungal activity of Curry leaves (Murraya koenigii)
Current Clinical and Medical EducationMurraya koenigii (L.) Spreng, commonly known as curry leaves, is a subtropical shrub belonging to the Rutaceae family, widely cultivated in India and other tropical regions for its aromatic leaves used in culinary applications.
Prakash Pant
doaj
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
In-vitro piscicidal activity and antifungal activity of Ageratum conyzoides
Current Clinical and Medical EducationAgeratum conyzoides L., a tropical invasive herb of the Asteraceae family, is traditionally used for its antimicrobial and insect-repellent properties across South America, Africa, and Asia.
Prakash Pant
doaj