Results 131 to 140 of about 4,358,031 (284)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Thicket of Diversity Pamphlet

, 2019
Fundraising pamphlet for the Big Thicket Association's "Thicket of Diversity" All Taxa Biodiversity Inventory of Big Thicket National Preserve projectThe Big Thicket Collection contains materials relating to the conservation of the Big Thicket area of ...
Big Thicket Association
core   +1 more source

Enhancing responsible production and sustainable clean water supply: applying OEE and six big losses analysis in environmental engineering

IOP Conference Series: Earth and Environmental Science
Abstract This study aimed to identify production losses that occur in the Clearator Unit in one of the state-owned drinking water treatment companies so that the implementation of improvements can increase the effectiveness of the process.
Yenny Sari, Muhammad Rosiawan, Rifda Aulia, Edy Purwanto   +3 more
openaire   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Integrasi Overall Equipment Effectiveness (OEE) dan Six Big Losses sebagai Upaya Peningkatan Kinerja Mesin Rolling

Factory Jurnal Industri, Manajemen dan Rekayasa Sistem Industri
Mesin rolling otomatis merupakan peralatan utama dalam proses pembentukan rantang tunggal di UD Putra Delta. Berdasarkan pengamatan awal, kinerja mesin ini belum optimal dan ditandai dengan tingginya downtime serta penurunan kecepatan operasi yang berdampak pada pencapaian target produksi. Penelitian ini bertujuan mengevaluasi tingkat efektivitas mesin
Andy Kasum Dwy Cahyono, Rina Sri Wulandari   +1 more
openaire   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

ANALISIS USULAN KEBIJAKAN MAINTENANCE UNTUK MEMINIMALISIR SIX BIG LOSSES PADA MESIN CETAK WEB UNIMAN DENGAN METODE RELIABILITY CENTERED MAINTENANCE (RCM II) (Studi Kasus : PT Temprina Media Grafika Semarang) [PDF]

, 2018
Perkembangan teknologi dalam kegiatan produksi saat ini menggunakan mesin karena menghasilkan efisiensi lebih besar. Penggunaan mesin produksi memiliki keterbatasan masa pakai dan faktor kegagalan atau kerusakan yang menyebabkan kerugian dalam produksi ...
PURWANTI, DEWI
core  

Evaluation and Improvement of a Plastic Production System Using Integrated OEE Methodology: A Case Study

Management Systems in Production Engineering
Overall equipment effectiveness (OEE) is a key indicator to measure the effectiveness of production systems. This paper aims to evaluate and improve a plastic production line based on OEE evaluation.
ALMashaqbeh Sahar, Hernandez Eduardo Munive   +1 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source