Results 121 to 130 of about 208,922 (315)
Engineering Science and Technology, an International Journal, 2019 Wind farms equipped by Doubly-Fed Induction Generators (DFIG) should have two capabilities so that system operators can efficiently utilizes them. These capabilities include Fault-Ride-Through (FRT) and smoothing the output active power fluctuations ...
Mostafa Sedighizadeh +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
, 2023 Ema Yuliana Sari, 2023 “Penerapan Metode Failure Mode and Effect Analysis dan Perhitungan Overaal Equipment Effectiveness Untuk Meminimisasi Six Big Losses di Perusahaan Automotive (Studi Kasus PT.Sadiyah Cahaya Logam)” .
EMA YULIANA SARI, .
core
SENTRI: Jurnal Riset IlmiahDalam proses produksi mesin yang digunakan setiap hari, ditemukan kendala yang mengalami kerusakan berupa kelistrikan motor penggerak, overheating, bearing dan part sudah aus. Berdasarkan data sekunder terkait total waktu Total Produktive Maintenance
Rizqi Nurrahman Tri Sutrisno +2 more
semanticscholar +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
National Conference on Applied Business, Education, & Technology (NCABET)PT. Taco Anugrah Corporindo, a subsidiary of the TACO Group, manufactures interior building laminated materials, specifically High Pressure Laminate (HPL), located in Cikande, Serang Regency, Banten.
Rio Fani, Asih Setyo Rini, Siti Hanan
semanticscholar +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2022 PT. XYZ bergerak dalam bidang industri makanan kategori biskuit. Permasalahan banyak terjadi pada mesin packaging dengan losses time sebesar 784.647,5 menit.
Achmadi, Fuad +1 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source