Results 81 to 90 of about 4,358,031 (284)
J@ti Undip: Jurnal Teknik IndustriImproving Overall Equipment Effectiveness (OEE) On Cartoner Machine Using Six Big Losses In Pharmaceutical Company.This research aims to improve the Overall Equipment Effectiveness (OEE) of the Cartoner machine at a pharmaceutical manufacturing facility ...
Anastasia Lidya Maukar +1 more
doaj +1 more source
PT. XYZ is a company that has a problem with one of its filling machines experiencing a process failure, resulting in waste. The aim of this research is to analyze the level of machine effectiveness using the overall equipment effectiveness method and identify factors that influence effectiveness by identifying the six big losses and developing ...
Yusuf Gustri Alfari, Hana Catur Wahyuni
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Jurnal Optimasi Sistem Industri, 2016 PT Semen Padang is a company that produces cement and it can not be separated from issues related to the effectiveness of the machinery/ equipment caused by factors such as six big losses.
Andita Rahayu
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
ANALISIS KEEFEKTIFAN MESIN MENGGUNAKAN METODE OEE DAN SIX BIG LOSSES DI CV. CIPTA KARYA MANDIRI PEMBUATAN FILTER [PDF]
, 2021 Improper machine maintenance and handling can cause a decrease in the level of engine performance which results in reduced engine effectiveness and productivity. Filter making company is a company engaged in manufacturing filters.
AVICHENA, MUHAMMAD HARIS INDRA
core
Analysis of Machine Effectiveness to Minimize Six Big Losses in the Palm Oil Industry
Semesta TeknikaPT XYZ is oil industry that processes CPO from oil palm, with a daily production target of 1,000 tons and a flow rate of 41.67 tons per hour. However, in 2019, the actual flow rate fell short of expectations. This study aims to improve equipment effectiveness in the refinery division through enhanced machine maintenance. Using the OEE method, the study
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Rekayasa MesinPT.MJF is a pharmaceutical company engaged in livestock pharmaceuticals and produces several products. One of its sub-units is engaged in maintenance, producing vaccines, and sterilizing pharmaceutical equipment.
Redi Nuranto +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source