Results 91 to 100 of about 4,358,031 (284)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Electronic and visual identification devices for adult goats reared in semi-intensive system

open access: yesRevista Brasileira de Zootecnia, 2014
This study intended to evaluate three identification devices for adult goats reared in semi-intensive system. They were (1) the ruminal bolus, electronic identification device composed of non-toxic ceramic and weighing 74.4 g; (2) small ear tag on left ...
Luciana Helena Kowalski   +6 more
doaj   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Analisis Mesin CNC Milling dengan Metode Overall Equipment Effectiveness dalam Mendeteksi Six Big Losses di PT. A [PDF]

open access: yes
PT. A is a company engaged in the manufacturing industry with products produced in the form of (dies, jigs, and parts manufacturing). During the activity, the CNC milling machine Milltex Vex 580b experienced engine damage which resulted in the machine ...
Azizah, Fahriza Nurul   +2 more
core   +1 more source

ANALISIS PRODUKTIVITAS MESIN FILLING K-201 DENGAN MENGGUNAKAN METODE OVERALL EQUIPMENT EFFECTIVENESS DAN SIX BIG LOSSES PADA PT JX NIPPON OIL & ENERGY LUBRICANT INDONESIA

open access: yesJournal of Industrial Engineering and Operation Management
Dalam mencapai kelancaran proses produksi perusahaan tentunya memerlukan dukungan dari berbagai aspek meliputi perawatan dan ketersediaan mesin yang selalu dapat digunakan secara optimal.
Muhammad Andi Zulfikar   +1 more
doaj   +1 more source

Preventive maintenance approach for improving the efficiency of SCM Olimpic K-800 Auto Edgeband machine [PDF]

open access: yesEPJ Web of Conferences
This study aims to improve the efficiency of the SCM Olimpic K-800 Auto Edgeband machine at PT ABC, a furniture manufacturing company. From January to June 2024, frequent machine breakdowns disrupted production flow and reduced productivity.
Indriartiningtias Retno   +5 more
doaj   +1 more source

Analysis of the Overall Equipment Effectiveness (OEE) to Minimize Six Big Losses of Pulp Machine: A Case Study in Pulp and Paper Industries

open access: yesIOP Conference Series: Materials Science and Engineering, 2019
Abstract Overall Equipment Effectiveness (OEE) is a method of measuring the usage effectiveness of the equipment. This method is known as an application of a Total Productive Maintenance (TPM) program. The ability to clearly identify the source of problem and it causal factors is the main advantage of this method since the improvement ...
M Sayuti   +3 more
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Enhancing FRT performance and smoothing output power of DFIG wind farm equipped by SFCL and SMES in a fuzzy framework

open access: yesEngineering Science and Technology, an International Journal, 2019
Wind farms equipped by Doubly-Fed Induction Generators (DFIG) should have two capabilities so that system operators can efficiently utilizes them. These capabilities include Fault-Ride-Through (FRT) and smoothing the output active power fluctuations ...
Mostafa Sedighizadeh   +2 more
doaj   +1 more source

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