Results 71 to 80 of about 4,558,823 (350)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Peningkatan kualitas dan efisiensi pada proses produksi dunnage menggunakan metode lean six sigma (Studi kasus di PT. XYZ)

Teknika, 2020
PT. XYZ merupakan industri manufaktur dalam bidang pembuatan dunnage. Dalam proses produksinya, masih ditemukan pemborosan yang mengakibatkan cacatan pada produk dunnage.
Asep Ridwan, Faula Arina, Ardi Permana
doaj   +1 more source

Application of Fuzzy Multi-Criteria Decision Making Methods on Six Sigma Projects Selection [PDF]

, 2017
. Six sigma method widely applied in production and service businesses is known as a project-oriented method. In six sigma method, selection of the prior project among others can be considered as a multi -criteria decision making problem.
ÇAKIR, Engin
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

ANALISIS PENGENDALIAN KUALITAS PROSES PENGANTONGAN SEMEN

Journal of Engineering and Management in Industrial System, 2016
PT. Semen Indonesia (Persero), Tbk is a leading cement producer. So the need to apply a good quality control system on all of its products and service to customers throughout the process.
Dwi Hadi Sulistyarini, Amanda Nur Cahyawati   +1 more
doaj   +1 more source

Lean Six Sigma Leadership in Health Care Organizations [PDF]

, 2017
The reason for choosing this topic was the want to change the current employee settings in health care organizations. Using Lean Six Sigma Leadership has been a proven method to increasing staff satisfaction and empowering lifelong learning. The research
Bittles, Natalie
core   +2 more sources

A Systematic Study of Neutrino Mixing and CP Violation from Lepton Mass Matrices with Six Texture Zeros

, 2004
We present a systematic study of 400 combinations of the charged lepton and neutrino mass matrices with six vanishing entries or texture zeros. Only 24 of them, which can be classified into a few distinct categories, are found to be compatible with ...
Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Fritzsch, Fukugita, Group, Jarlskog, Klapdor-Kleingrothaus, Ramond, references, See, See, See, See, Shun Zhou, Xing, Xing, Xing, Yanagida, Zee, Zhi-zhong Xing   +22 more
core   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Six Sigma in Human Resource Management of Selected Organisation in Bangalore [PDF]

, 2014
The aim of the study is to examine the six sigma practices and its impact on strategic decision. Six sigma as a business process is now allowing organizations to improve their bottom line by designing and monitoring business activities in a way that ...
Rajesha, S.
core