Results 191 to 200 of about 158,975 (248)

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Fluorescence-detection size-exclusion chromatography specifically detects autoantibodies targeting the ganglionic acetylcholine receptor in patients with autoimmune autonomic ganglionopathy. [PDF]

J Neuroimmunol
Baxter L, Hopkins S, O'Connor KC, Pham MC, Nowak RJ, Monson NL, Blackburn K, Hibbs RE, Vernino S, Noviello CM.   +9 more
europepmc   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

Mechanistic Modeling of Size Exclusion Chromatography-Assisted In Vitro Refolding of the Recombinant Biosimilar Teriparatide (PTH-34). [PDF]

ACS Omega
Ughade S, Rana S, Nadeem M, Kumthekar R, Mahajani S, Bhambure R.   +5 more
europepmc   +1 more source

Size-Exclusion Chromatography: A Path to Higher Yield and Reproducibility Compared to Sucrose Cushion Ultracentrifugation for Extracellular Vesicle Isolation in Multiple Myeloma. [PDF]

Int J Mol Sci
Grenhas M, Lopes R, Ferreira BV, Barahona F, João C, Carneiro EA.   +5 more
europepmc   +1 more source

Distinct molecular properties and functions of small EV subpopulations isolated from human umbilical cord MSCs using tangential flow filtration combined with size exclusion chromatography. [PDF]

J Extracell Vesicles
Liu W, Wang X, Chen Y, Yuan J, Zhang H, Jin X, Jiang Y, Cao J, Wang Z, Yang S, Wang B, Wu T, Li J.   +12 more
europepmc   +1 more source

Affinity-Resolved Size Exclusion Chromatography Coupled to Mass Spectrometry: A Novel Tool to Study the Attribute-and-Function Relationship in Therapeutic Monoclonal Antibodies. [PDF]

Anal Chem
Yan Y, Xing T, Huang X, Peng W, Wang S, Li N.   +5 more
europepmc   +1 more source

Fast insights into chitosan-cleaving enzymes by simultaneous analysis of polymers and oligomers through size exclusion chromatography. [PDF]

Sci Rep
Hellmann MJ, Moerschbacher BM, Cord-Landwehr S.   +2 more
europepmc   +1 more source

Correction to Distinct Molecular Properties and Functions of Small EV Subpopulations Isolated From Human Umbilical Cord MSCs Using Tangential Flow Filtration Combined With Size Exclusion Chromatography. [PDF]

J Extracell Vesicles
europepmc   +1 more source

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Size Exclusion Chromatography

1999
SEC is a standard technique that is frequently used to determine MMD of polymers and the corresponding number, weight, and z averages, Mn, Mw, and Mz. As has already been mentioned in Section 2.2, the separation in SEC is governed by entropic effects, unlike other modes of liquid chromatography, where enthalpic effects are predominant.
Sadao Mori, Howard G. Barth
  +4 more sources