Results 111 to 120 of about 9,243,590 (311)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Commissioned piece of creative autobiographical writing produced for the Ardtornish Retreat (RC1) in partnership with Scottish Book Trust 2014. The text is thematically focused on 'love' and actively searches for the 'magical' within the natural world ...
Richards, J
core
Antinomie dialettiche nel De magnanimitate di Giovanni Pontano
Il De magnanimitate di Giovanni Pontano, maestro riconosciuto dell’Umanesimo aragonese, si apre con un’articolata definizione della magnanimitas, virtù connaturata ai regnanti che corrisponde alla μεγαλοψυχία aristotelica.
Giuseppe Zeccato
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Employer Size Effects in Russia [PDF]
As early as 1911, Henry L. Moore documented that the wages of female textile workers in Italy were higher in larger establishments. In the last thirty years a large number of studies have demonstrated the presence of employer size-wage effects (at both ...
Todd Idson
core
Size-exclusion chromatography.
Size-exclusion chromatography of IFABP (solid line), Δ98Δ (dashed line) and Δ78Δ (dotted line). Proteins were sampled onto a Superdex-75 column and eluted at 10% v/v TFE in buffer PN8 (see Materials and methods).
José M. Delfino (736126) +3 more
core +1 more source
«So scudo e lancia adoperare anch’io»: Marfisa donna e cavaliere
Il contributo intende studiare il personaggio di Marfisa nell’Inamoramento de Orlando di Matteo Maria Boiardo e nell’Orlando furioso di Ludovico Ariosto, con alcuni accenni alla Marphisa bizarra di Giovan Battista Dragoncino da Fano (1531).
Rosario Carbone
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

