Results 121 to 130 of about 10,587,170 (260)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Size-Dependent Sensitivity of Aquatic Insects to Metals
, 2019 Laboratory assessments of aqueous metal toxicity generally demonstrate aquatic insects tolerate relatively high concentrations of metals in aqueous exposures; however, mesocosm experiments and field biomonitoring often indicate effects at relatively low ...
Christopher J. Kotalik (5953403) +5 more
core +1 more source
Scientific ReportsThe aim of this study was to investigate the measurement of the incident angle of the main blood vessel, and the benefits of its integral with ultrasound malignant features of breast nodules for the assessment of breast malignancy based on BI-RADS.
Kailiang Chen, Size Wu
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Firm Size and Export Intensity [PDF]
This paper presents a unifying theory, explaining the different relationships between firm size and export intensity that have been found in previous studies.
Donkers, A.C.D., Verwaal, E.
core
, 2023 Commissioned piece of creative autobiographical writing produced for the Ardtornish Retreat (RC1) in partnership with Scottish Book Trust 2014. The text is thematically focused on 'love' and actively searches for the 'magical' within the natural world ...
Richards, J
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Be extra skeptical of class-size skeptics
, 2002 Some say reduced class size isn't ...
Palo Alto Weekly
core
Size-fecundity relationships across temperature and resource treatments.
, 2018 (A) Size-fecundity relationships of A. albopictus across temperature treatments (N = 360). (B) Size-fecundity relationships of A. albopictus across resource treatments (N = 386).
Katie S. Costanzo (130597) +2 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source