Results 51 to 60 of about 43,308,262 (294)
Prenatal factors affecting the probability of survival between birth and weaning in rabbits
The aim of this study was to analyse the relationships between kit birth weight and litter size with kit survival from birth to weaning, and to estimate the effects of place of birth, nest quality, cannibalism, lactation, parity order, season and sex.
Rafik Belabbas +9 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On February 11th 2007, 13 neonates and 4 adults of Cephalurus cephalus were collected using a benthic sledge, during one oceanographic cruise (Talud X, St. 12) in the mid Gulf of California, Mexico (28°01'36" N, 111°51'50" W). The lollipop catsharks were
Hugo Aguirre-Villaseñor +1 more
doaj
Background Small size at birth is an important indicator of neonatal health and survival, particularly in low- and middle-income countries. It is a preventable public health problem linked with higher risks of infant mortality and developmental delays ...
Dondo Jagusa Aatsav +14 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Birth size and breast cancer risk: Re-analysis of individual participant data from 32 studied [PDF]
Background Birth size, perhaps a proxy for prenatal environment, might be a correlate of subsequent breast cancer risk, but findings from epidemiological studies have been inconsistent.
Collaborative, GOP-NRFASROBC +3 more
core
Dawit Habte Woldeyes,1 Mengstu Desalegn Kiros,1 Belta Asnakew Abegaz,1 Ashenafi Abate Woya2 1Anatomy Unit, Department of Biomedical Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia; 2Department of Statistics ...
Woldeyes DH +3 more
doaj
Assessing reproductive performance and predictive models for litter size in Landrace sows under tropical conditions [PDF]
Objective Litter size and piglet loss at birth significantly impact piglet production and are closely associated with sow parity. Understanding how these traits vary across different parities is crucial for effective herd management.
Praew Thiengpimol +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

