Results 71 to 80 of about 43,308,262 (294)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

On a size-structured two-phase population model with infinite states-at-birth [PDF]

, 2009
In this work we introduce and analyze a linear size-structured population model with infinite states-at-birth. We model the dynamics of a population in which individuals have two distinct life-stages: an "active" phase when individuals grow, reproduce ...
Farkas, Jozsef Zoltan, Centre de Recerca Matemàtica, Hinow, Peter, Farkas, József Z.   +3 more
core   +1 more source

Determinant factors of under-five mortality in Southern Nations, Nationalities and People’s region (SNNPR), Ethiopia

Italian Journal of Pediatrics, 2021
Background Child mortality is a key indicator of the performance of the health system of a nation. Impressive progress in the reduction of under-five mortality has been made in Ethiopia.
Gizachew Gobebo
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Birth data accessibility via primary care health records to classify health status in a multi-ethnic population of children: an observational study. [PDF]

, 2015
Access to reliable birth data (birthweight (BW) and gestational age (GA)) is essential for the identification of individuals who are at subsequent health ...
Fothergill, H, Fothergill, Helen, Wade, Angela, Harding, Seeromanie, Lum, S, Bonner, R, Harding, Seeromanie; id_orcid, Stocks, Janet, Stocks, J, Lum, Sooky, Sears, David, Wade, A, Bonner, Rachel, Bountziouka, Vassiliki, Slevin, H; id_orcid, Bountziouka, V, Sears, D, Griffiths, Chris, Slevin, Hannah, Harding, S, Griffiths, C, Slevin, H   +21 more
core   +1 more source

Snus in pregnancy and infant birth size: a mother–child birth cohort study

ERJ Open Research, 2019
Rationale While recent studies show that maternal use of snus during pregnancy is increasing, the potential effects on infant birth size is less investigated, with conflicting results.
Ina Kreyberg, Katarina Hilde, Karen Eline S. Bains, Kai-Håkon Carlsen, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Christine M. Jonassen, Live S. Nordhagen, Björn Nordlund, Corina S. Rueegg, Katrine D. Sjøborg, Håvard O. Skjerven, Anne C. Staff, Riyas Vettukattil, Karin C. Lødrup Carlsen, the PreventADALL Study Group   +16 more
doaj   +1 more source

The impact of dietary diversity and seasonality in food availability on the quantile distribution of birth size among pregnant women in rural Malawi – a cross-sectional study

BMC Pregnancy and Childbirth, 2022
Background Dietary diversity scores can be used as a proxy for dietary intakes and for assessment of nutrient adequacy. Studies from low-resource settings have found maternal dietary diversity scores to be associated with neonatal birth size.
Katrine G. Hjertholm, Gerd Holmboe-Ottesen, Ibrahimu Mdala, Zumin Shi, Per O. Iversen   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

DETERMINANTS OF LOW BIRTH WEIGHT: COMPARISON BETWEEN PERCEPTION AND RECORDS USING THE INDONESIAN DEMOGRAPHIC HEALTH SURVEY DATA

Jurnal Biometrika dan Kependudukan
Measuring birth weight in low resource settings is problematic. Mothers' perception of newborn's size is often used as a proxy. This study examines the correlation between weight measured at birth and the mother's perception of her child's size and ...
Ahmad Ridoi Yuda Prayogi, Susy Katikana Sebayang, Mu Li   +2 more
doaj   +1 more source

Violence during pregnancy: Determinants and association with small size of baby at birth [PDF]

Journal of Sharif Medical & Dental College, 2016
Objective: Intimate partner violence (IPV) is a global health concern. The aim of this study was to determine whether there is an association between IPV and the size of child at the time of birth. Methodology: A systematic data collected from Pakistan
Muhammad Anwar Sulehri, Younas Mehrose, Madiha Anwar Sulehri, Rabia Anwar   +3 more
doaj