Results 121 to 130 of about 10,678,514 (290)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The Effect of Size and Crumb Rubber Composition as a Filler with Compatibilizer Pp-g-ma in Polypropylene Blends and Sir-20 Compound on Mechanical and Thermal Properties [PDF]
, 2012 Having been researched the development of thermoplastic elastomer material of polypropylene and natural rubber SIR-20 compound with Crumb Rubber as the filler. Reinforced polypropylene with size 60 mesh with 1 mm, and the composition of the Crumb rubber (
Frida, E. (Erna)
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Revista IBRACON de Estruturas e MateriaisConsidering the physical nonlinearity of concrete and the fundamentals of fracture mechanics for quasi-brittle materials, the objective of this study was to determine the fracture energy and the length of the fracture process zone (FPZ) as well as the ...
G. O. RIBEIRO, P. C. GUETTI, P. SERNA
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The Size Effect of Shear Bands in Dense Sands—A Discrete Element Analysis
Applied SciencesThe localization of deformation in shear bands is a fundamental phenomenon in granular materials like soil. In this study, we focus on the characteristics of shear bands, particularly the size effect, by implementing biaxial discrete element method (DEM)
Zongyuan Mao +3 more
doaj +1 more source
Citation: 'size effect' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08874 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source