Results 61 to 70 of about 18,225,520 (262)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-01-18-2019

, 2019
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-06-01-2007

, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Application of FEA in press size determination in the production of an aluminum monolithic non-rotational component using deep drawing

Discover Applied Sciences
The success of a deep-drawing process largely depends on the selection of an appropriately sized press. Optimal press sizing is critical for ensuring component quality, cost efficiency, and process reliability.
Blessed Sarema, Stephen Matope, Matthias Nagel, Andreas Sterzing   +3 more
doaj   +1 more source

Effect of Formulation and Fermentation on Protein Structure, Nutritional Characteristics and Techno-Functional Properties of Hemp–Oat Press Cake Matrices

Foods
The valorization of plant-based press cakes as sustainable food ingredients requires understanding how formulation and processing affect their properties.
Erika Keiko Martinez Vargas, Alvija Šalaševičienė, Per Ertbjerg   +2 more
doaj   +1 more source

Datasets for supplier selection and order allocation with green criteria, all-unit quantity discounts and varying number of suppliers

Data in Brief, 2017
This data article provides detailed optimization input and output datasets and optimization code for the published research work titled “Dynamic green supplier selection and order allocation with quantity discounts and varying supplier availability ...
Sadeque Hamdan, Ali Cheaitou
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-07-20-2007

, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Effect of different granulation processes and powder particle sizes on uniformity of diamond distribution in the mixed powder

Jin'gangshi yu moliao moju gongcheng
ObjectivesWith the rapid development of diamond tool quality and varieties, the requirements for diamond tool properties are increasingly rigorous, and the uniformity of diamond distribution in diamond tools is an important index affecting its ...
Zhenghui MA, Ting HU, Wen LUO, Zhi FANG, Feng LUO   +4 more
doaj   +3 more sources