Results 131 to 140 of about 34,933 (276)

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus

Andrology, EarlyView.
ABSTRACT Background Lichen sclerosus is a chronic, inflammatory, scarring disease of the skin that manifests mostly in the genital region. Objective We studied the histomorphological characteristics, grade, and pattern of inflammation in male pediatric patients with lichen sclerosus.
Valerie Flammang, Arndt Hartmann, Robert Stöhr, Katrin Weigelt, Carol Geppert, Frederik A. Stuebs, Matthias W. Beckmann, Bernd Wullich, Helge Taubert, Marios Marcou, Sven Wach   +10 more
wiley   +1 more source

THU0229 HSA-MIR-513C-3P OVEREXPRESSION DECREASES XBP-1S CORRELATING WITH INCREASED INFLAMMATION AND AUTOANTIBODIES IN SALIVARY GLANDS FROM SJÖGREN'S SYNDROME PATIENTS [PDF]

, 2020
Patricia Carvajal, Sergio Aguilera, Benjamín Heathcote, Isabel Castro, D. Jara, María‐José Barrera, V. Maracaja, Sergio González, Verónica Aliaga, Claudio Molina, María‐Julieta González   +10 more
openalex   +1 more source

Outcome parameters in studies investigating dry eye disease: A systematic literature review

Acta Ophthalmologica, EarlyView.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai, Doreen Schmidl, Liudmyla Petric, Patrick Janku, Theresa Lindner, Ulrich Graf, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfer   +8 more
wiley   +1 more source

IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy

Cancer Science, EarlyView.
IRF4 is a prognostic biomarker in cervical cancer. IRF4 enhances radiosensitivity and inhibits tumor growth via PI3K/AKT/mTOR‐mediated autophagy. IRF4 boosts radiation response in vitro and in vivo. ABSTRACT Interferon regulatory factor 4 (IRF4), a critical member of the IRF transcription factor family, harbors an elusive biological role in cervical ...
Meihui Gao, Zhaolei Cui, Huachun Song, Yanhong Li, Anyang Li, Jianfeng Zheng, Linying Liu, Xuefen Lin, Wankai Fu, Yang Sun   +9 more
wiley   +1 more source

Treatment of oral dryness related complaints (xerostomia) in Sjögren's syndrome [PDF]

, 1999
W. A. Van Der Reijden, Arjan Vissink, E.C.I. Veerman, A. van Nieuw Amerongen   +3 more
openalex   +1 more source

Implant Therapy in Patients With Neurodegenerative Diseases—A Scoping Review

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The increasing longevity of populations has resulted in a growing number of older adults requiring prosthodontic care, including those with neurodegenerative diseases (NDs). Neurodegenerative diseases pose significant challenges to prosthodontic care, and it remains unclear whether implant therapy in this population achieves ...
Lysandre David, Sabrina Maniewicz, Najla Chebib, Gabriel Gold, Murali Srinivasan, Frauke Müller   +5 more
wiley   +1 more source

Diagnostic Approaches to Sjögren’s Syndrome: a Literature Review and Own Clinical Experience

eJournal of Oral Maxillofacial Research, 2012
Objectives: The purpose of present paper is to critically address the recent advances on diagnostic procedures of Sjögren’s syndrome, taking into account the attained local and systemic features of the disease.
Pedro de Sousa Gomes, Gintaras Juodzbalys, Maria Helena Fernandes, Zygimantas Guobis   +3 more
doaj  

The salivary glands in Sjögren's syndrome : pathogenetic aspects of the initiation of sialoadenitis [PDF]

, 2001
Sjögren's syndrome is a chronic inflammatory disorder with autoimmune etiology, affecting primarily the salivary and lacrimal glands. In these glands. focallymphocytic infiltrates develop.
Blokland, S.C.A. (Saskia) van
core  

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Profiles of peripheral B cell subsets in a cohort of primary Sjögren's syndrome patients and their potential clinical significance

Journal of Dental Sciences
Background/purpose: Primary Sjögren's syndrome is a prototypical autoimmune disease, with B cell dysfunction as a dominant feature. Further insights into distribution of B cell subsets in primary Sjögren's syndrome are urgently required to identify the ...
Yixiao Xing, Boya Li, Pan Wei, Hong Hua
doaj   +1 more source