Results 91 to 100 of about 37,519 (224)

A randomized, double-blind, placebo-controlled clinical trial of fluoride varnish in preventing dental caries of Sjögren’s syndrome patients [PDF]

, 2016
published_or_final_versio
Leung, KCM, Leung, M.H., Lo, ECM, Mok, M.Y., Xin, W.N.   +4 more
core   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

EULAR Sjogren's syndrome disease activity index (ESSDAI):a user guide [PDF]

, 2015
The EULAR Sj\uf6gren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS.
A. Tzioufas, C. Vitali, E. Theander, H. Bootsma, J.-. Gottenberg, M. Ramos-Casals, P. Brito-Zeron, P. Ravaud, R. Caporali, R. Seror, S.J. Bowman, T. Dorner, X. Mariette   +12 more
core   +2 more sources

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

Arthritis &Rheumatology, Accepted Article.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López, Carlos Rangel‐Peláez, Inmaculada Rodriguez‐Martin, Alfredo Guillen‐Del‐Castillo, Carmen P Simeón‐Aznar, José L Callejas, International SSc Group; PRECISESADs Clinical Consortium, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries‐Bouwstra, Ariane L Herrick, Yannick Allanore, Marta E. Alarcon‐Riquelme, Lorenzo Beretta, Shervin Assassi, Christopher P Denton, Maureen D Mayes, Javier Martin, Marialbert Acosta‐Herrera, Martin Kerick   +23 more
wiley   +1 more source

Physical activity but not sedentary activity is reduced in primary Sjögren’s syndrome [PDF]

, 2016
The aim of the study was to evaluate the levels of physical activity in individuals with primary Sjögren’s syndrome (PSS) and its relationship to the clinical features of PSS.
Adeniba, R., Al-Ali, S., Andrews, J., Bacabac, E.C., Bombardieri, M., Bombardieri, M., Booth, A., Bowman, S.J., Brailsford, S., Carr, A., Carrozzo, M., Chakravarty, K., Clunie, G., Coady, D., Collins, K., Cooper, A., Cooper, A., Corbett, I., Cuckow, S., Dasgupta, B., Dimitroulas, T., Downie, C., Edgar, S., Emery, P., Emery, P., Field, A., Figuereido, F., Foggo, H., Gendi, N., Giles, I., Gordon, E., Griffiths, B., Gupta, M., Gupta, M., Hall, F., Hamburger, J., Hunter, J., Hunter, J., Isenberg, D., James, K., Jones, A., Jones, B., Kadiki, L., Kaur, D., Kaye, S., Kitas, G., Kitas, G.D., Knight, S., Lamabadusuriya, S., Lanyon, P., Lanyon, P., Lawson, C., Lendrem, D., Lloyd, M., Logan, J., MacKay, K., Macleod, I., Mawson, P., McHugh, N., McLaren, J., McManus, A., Mewar, D., Miller, A., Mitchell, S., Mitchell, S., Miyamoto, S.T., Moore, L., Moots, R., Moots, R.J., Muir, A., Mulherin, D., Natasari, A., Ng, W.F., Ortiz, G., Pease, C., Pease, C., Pitzalis, C., Pitzalis, C., Price, E., Price, E.J., Pugmire, S., Rauz, S., Regan, M., Regan, M., Richards, A., Rose, G., Stirton, L., Stocks, P., Sutcliffe, N., Sutcliffe, N., Symmons, D., Tarn, J., Trenell, M., Vadivelu, S., Vadivelu, S., Watkins, M., White, P., Young-Min, S., Young-Min, S.A.   +98 more
core   +6 more sources

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Peripheral regulatory cells immunophenotyping in Primary Sjögren's Syndrome: a cross-sectional study [PDF]

, 2013
INTRODUCTION: IL-10--producing B cells, Foxp3-expressing T cells (Tregs) and the IDO-expressing dendritic cells (pDC) are able to modulate inflammatory processes, to induce immunological tolerance and, in turn, to inhibit the pathogenesis of autoimmune ...
Gabriela Hernández-Molina, Guadalupe Lima, Janette Furuzawa-Carballeda, Karen Férez-Blando, Luis Llorente, Yahaira Rivera-Vicencio   +5 more
core   +1 more source

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Efficacy of Cevimeline on Xerostomia in Sjögren's Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Current Therapeutic Research
Background: Xerostomia, or dry mouth, is a common and debilitating symptom in patients with Sjögren's syndrome, affecting their quality of life. Although Cevimeline, a muscarinic agonist, has been investigated as a potential treatment, its efficacy and ...
Mehdi Karimi, MD, Fatemeh Ahmadi Hajikolaei, MD, Fahime Hoseinpour, MD, Seyed-Ali Hashemi, MD, Anita Fatehi, MD, Seyed-Abbas Pakmehr, MD, Niloofar Deravi, MD, Mahdyieh Naziri, MSc, Mohaddeseh Belbasi, MD, Sahar Khoshravesh, MD, Seyed Hossein Vaezzadeh, MD   +10 more
doaj   +1 more source