Results 71 to 80 of about 34,324 (282)

Modulation of c-Jun NH2-Terminal (JNK) by Cholinergic Autoantibodies from Patients with Sjögren’s Syndrome [PDF]

open access: yes, 2011
Background: We wanted to determine (via an immunopharmacological approach) whether the c-Jun NH2 terminal kinase (JNK) cascade is phosphorylated in the submandibular gland by carbachol and cholinergic autoantibodies (IgG) present in the sera of patients ...
Borda, Enri Santiago   +3 more
core   +1 more source

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian   +11 more
wiley   +1 more source

Evolution of diagnostic criteria for Sjögren′s Syndrome

open access: yes口腔疾病防治, 2019
Sjögren′s syndrome lacks a single and objective diagnostic index, and its diagnosis often requires compre⁃ hensive analysis according to classification criteria.
TAO Qian, LIANG Peisheng
doaj   +1 more source

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

open access: yes, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter   +3 more
core   +1 more source

Lacrimination in Sjogren′s syndrome. Is Schirmer′s test really a useful diagnostic tool?

open access: yesIndian Journal of Ophthalmology, 1988
In the past, Schinier′s test was used as a diagnostic tool in Sjogren′s Syndrome. In this study, a comparison of 100 normal patients with 2l patients with Sjogren′s Syndrome has been made to study its reliability.
Bhadoria D   +3 more
doaj  

The relationship of the prevalence and severity of restless legs syndrome in primary Sjögren syndrome with insomnia status, anxiety, depression, and neuropathic pain

open access: yesEgyptian Rheumatology and Rehabilitation, 2023
Background and aims In this study, we aimed to compare the prevalence of restless legs syndrome (RLS) between primary Sjögren syndrome (PSS) patients and the healthy population and investigate the relationships between RLS and insomnia status, anxiety ...
Meliha Kasapoğlu Aksoy   +3 more
doaj   +1 more source

Dental implants in patients with oral mucosal alterations : an update [PDF]

open access: yes, 2011
Objective: To determine whether a series of diseases of the oral mucosa - Sjögren syndrome, ectodermal dysplasia, epidermolysis bullosa and lichen planus - reduce the survival rate of dental implants. Material and Method: A Medline search was carried out
Ata-Ali Mahmud, Francisco Javier   +4 more
core   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

One patient with Sjogren’s syndrome presenting schizophrenia-like symptoms

open access: yesNeuropsychiatric Disease and Treatment, 2016
Ching-En Lin1,2 1Department of Psychiatry, Taipei Tzu-Chi Hospital, Buddhist Medical Foundation, Taiwan, Republic of China; 2School of Medicine, Tzu-Chi University, Hualien, Taiwan, Republic of China Abstract: Comorbid depression in patients with ...
Lin C
doaj  

Sjogren′s syndrome

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2008
Sjogren′s syndrome (SS) is a chronic autoimmune disorder. It is characterized by dysfunction and destruction of exocrine glands associated with lymphocytic infiltrates and immunological hyperactivity.
Ankur Jethlia   +2 more
doaj   +1 more source

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