Results 131 to 140 of about 994,709 (302)

Chronic kidney disease and denosumab in metastatic bone disease: A multicenter Turkish cohort study on severe hypocalcemia, skeletal events, and survival

Journal of Bone Oncology
Background: Denosumab, a monoclonal antibody against receptor activator of nuclear factor kappa-B ligand (RANKL), is widely used to prevent skeletal-related events (SREs) in patients with bone metastases from solid tumours.
Halil İbrahim Ellez, Hüseyin Salih Semiz, Ferhat Ekinci, Atike Pınar Erdoğan, Fatih Kuş, Fatih Karataş, Ertuğrul Bayram, Kubilay Karaboyun, Havva Yeşil Çınkır, Nilgün Yıldırım, Melek Karakurt Eryılmaz, Esma Türkmen Bekmez, Özkan Alan, Melike Özçelik, Yakup Düzköprü, Teoman Şakalar, Naziye Ak, Yusuf İlhan, Tuğba Yavuzşen, Nazım Serdar Turhal   +19 more
doaj   +1 more source

Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]

, 2019
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico, Bertoli, Alessandro, Buson, Lisa, Cagnin, Stefano, Chemello, Francesco, Grespi, Francesca, Lanfranchi, Gerolamo, Martini, Paolo, Massimino, Maria L, Millino, Caterina, Pacchioni, Beniamina, Peggion, Caterina, Romualdi, Chiara, Scorrano, Luca   +13 more
core   +1 more source

Healthcare resource utilisation associated with skeletal‐related events in European patients with multiple myeloma: Results from a prospective, multinational, observational study

European Journal of Haematology, 2018
Patients with multiple myeloma (MM) often experience debilitating skeletal‐related events (SREs: pathologic fracture, radiation to bone [RB], surgery to bone [SB] or spinal cord compression [SCC]).
J. Ashcroft, I. Durán, H. Hoefeler, V. Lorusso, D. Lueftner, M. Campioni, M. Intorcia, A. Bahl   +7 more
semanticscholar   +1 more source

All‐Aqueous Pullulan Fibers Enabling Visible‐to‐Near‐Infrared Waveguiding with Mechanical and Thermal Resilience

Advanced Functional Materials, EarlyView.
Pullulan, a biomass‐derived polysaccharide, is transformed into transparent optical fibers using a solvent‐free borax hydrogel‐spinning method. The fibers outperform PMMA with ≈200 MPa tensile strength and 200 °C stability, while uniquely guiding visible‐to‐NIR light and enabling additive‐free humidity sensing.
Yuya Fukata, Aayush Kumar Jaiswal, Ari Hokkanen, Hannes Orelma, Tadahisa Iwata   +4 more
wiley   +1 more source

Metastatic bone disease: Pathogenesis and therapeutic options

Journal of Bone Oncology, 2019
Bone metastases (BM) are a common complication of cancer, whose management often requires a multidisciplinary approach. Despite the recent therapeutic advances, patients with BM may still experience skeletal-related events and symptomatic skeletal events,
Stella D'Oronzo, Robert Coleman, Janet Brown, Francesco Silvestris   +3 more
doaj   +1 more source

MP55-16 SKELETAL-RELATED EVENTS IN PATIENTS WITH BONE-METASTATIC CARCINOMA OF THE BLADDER OR UPPER URINARY TRACT [PDF]

, 2020
Nima Almassi, Imaani Easthausen, Soleen Ghafoor, Paul J. Christos, Timothy F. Donahue, Jacob Rosenberg, Azeez Farooki   +6 more
openalex   +1 more source

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]

, 2009
Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Anderson, Anja Niehoff, Balcerzak, Balcerzak, Belluoccio, Bent Brachvogel, Berendes, Blumbach, Brachvogel, Brachvogel, Brachvogel, Bradford, Budde, Christian Frie, Collett, Damazo, Daniele Belluoccio, DiCesare, Ernst Pöschl, Friedericke Pausch, Genge, Genge, Gerke, Girkontaite, Haut Donahue, Hawkins, Hazarika, Hikiji, Hofmann, Ivan Grskovic, John F Bateman, Julia Etich, Karsenty, Karsenty, Kim, Kirsch, Kirsch, Kirsch, Koopman, Kwan, Ling, Livak, Morgan, Murshed, Pfaffl, Rety, Romeis, Sabrina Rosenbaum, Schmitz, Srivastava, Srivastava, Stephen E Moss, Ursula Schlötzer-Schrehardt, Van Gelder, White   +54 more
core   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

Future of bisphosphonates and denosumab for men with advanced prostate cancer

Cancer Management and Research, 2014
Maryam Iranikhah, Steve Stricker, Maisha Kelly Freeman Samford University, McWhorter School of Pharmacy, Birmingham, AL, USA Abstract: Prostate cancer is the most common cancer occurring in American men of all races.
Iranikhah M, Stricker S, Freeman MK
doaj  

Micro and Nanostructural Diversity of Lizard Osteoderm Capping Tissue in Relation to Mechanical Performance

Advanced Functional Materials, EarlyView.
This study shows that lizard osteoderm capping tissue is a hyper‐mineralized hydroxyapatite layer consistently covering the superficial osteoderm surface in those species studied here, yet it varies greatly in morphology, nanostructure, and mechanical performance across species.
Adrian Rodriguez‐Palomo, Marius Didziokas, Malene Siri Berg Jacobsen, Thorbjørn Erik Køppen Christensen, Innokenty Kantor, Mads Ry Vogel Jørgensen, Klaus Pagh Almtoft, Jesper Skovhus Thomsen, Anthony Herrel, Catherine J.A. Williams, Henrik Birkedal   +10 more
wiley   +1 more source