Results 281 to 290 of about 386,289 (317)
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen +7 more
wiley +1 more source
Predictors of skeletal-related events in lung cancer with bone metastases
A. Villemain
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Managing skeletal related events resulting from bone metastases
BMJ, 2008#### Summary points Pain is one of the most common symptoms managed in a palliative setting, and over half of all metastatic cancers will be associated with pain originating from bone metastases. Breast, lung, and prostate cancers account for about 80% of all bone metastases.1 Management of bone pain is especially important in patients with prostate ...
Anna N, Wilkinson +2 more
openaire +2 more sources
Pharmacologic Prevention of Skeletal-Related Events in Cancer Patients
Orthopedics, 2010Intravenous bisphosphonates are a standard therapeutic option in the prevention of skeletal-related events in metastatic breast and prostate cancer as well as multiple myeloma with bone involvement. Denosumab represents a new class of medications that inhibits the RANK ligand and is currently being evaluated to prevent skeletal-related events.
Sal, Bottiglieri +2 more
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Beyond Skeletal-Related Events
European Urology Supplements, 2006Abstract Objectives Zoledronic acid may have potential antitumor activity; it is the most active agent among the bisphosphonates in blocking the prenylation (activation) of small signaling proteins required for cell function and survival. This presentation discusses the results of preclinical studies evaluating the antitumor activity of zoledronic ...
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The Pharmacological Management of Skeletal-Related Events From Metastatic Tumors
Orthopedics, 2009Bone is one of the most common sites of metastatic disease from cancer, affecting around 400,000 patients each year. Skeletal-related events (SRE) include hypercalcemia, fractures, spinal cord compression or severe bone pain and may occur as a complication of metastasis.
Anna, Hitron, Val, Adams
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Predicting Skeletal-related Events Using SINS
SpineStudy Design. Predictive study utilized retrospectively collected data. Objective. The primary objective was to evaluate the predictive association between the Spine Instability Neoplastic Score (SINS) and Skeletal-related events (SREs).
Kazuo, Nakanishi +6 more
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Impact of skeletal-related events on multiple myeloma treatment.
Journal of Clinical Oncology, 2018e20009Background: Skeletal-related events (SREs), sequelae of bone lesions, are common and devastating complications in patients with multiple myeloma (MM).This study assessed the impact of SREs on...
Debajyoti Bhowmik +5 more
openaire +1 more source
Skeletal-Related Events In Myeloma: A Population-Based Study
Blood, 2013Abstract Introduction New therapies have resulted in improvements in myeloma survival, with increasing numbers of patients receiving treatment over several years. Despite this progress, the remitting and relapsing course of the disease continues to be associated with increases in patient morbidity and
John Ashcroft +9 more
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