Results 281 to 290 of about 994,709 (302)

Comprehensive Clinical Literature Review of Managing Bone Metastases in Breast Cancer: Focus on Pain and Skeletal-Related Events.

Clinical Journal of Oncology Nursing, 2023
BACKGROUND Bone metastases are the most common site of metastatic disease in breast cancer and can result in significant pain and an increased risk of skeletal-related events (SREs). Uncontrolled pain can further lead to negative outcomes.
K. Hamash, Suzanne L Walker
semanticscholar   +1 more source

Intervention with the Bone-Associated Tumor Vicious Cycle through Dual-Protein Therapeutics for Treatment of Skeletal-Related Events and Bone Metastases.

ACS Nano, 2022
Bone metastasis is a common metastasis site such as lung cancer, prostate cancer, and other malignant tumors. The occurrence of bone metastases of lung cancer is often accompanied by bone loss, fracture, and other skeletal-related events (SREs) caused by
Yimin Niu, Hongbin Yang, Zhenyan Yu, Cuicui Gao, Shuaishuai Ji, Jie Yan, Lei Han, Q. Huo, Ming Xu, Yang Liu   +9 more
semanticscholar   +1 more source

Repurposing denosumab in lung cancer beyond counteracting the skeletal related events: an intriguing perspective

Expert Opinion on Biological Therapy, 2020
Introduction Repurposing denosumab in lung cancer therapeutics capitalizes on its well-established role in preventing the skeletal related events (SREs) and its emerging, yet elusive, bone-independent role, assigned to inhibit the contribution of RANKL ...
M. Deligiorgi, D. Trafalis
semanticscholar   +1 more source

Factors associated with skeletal‐related events in patients with bone metastatic melanoma: A retrospective study of 481 patients

Journal of Surgical Oncology
Metastatic bone disease is estimated to develop in up to 17% of patients with melanoma, compromising skeleton integrity resulting in skeletal‐related events (SREs), which impair quality of life and reduce survival.
Michelle R. Shimizu, T. D. de Groot, P. K. Twining, Tim Kobes, M. Ferrone, K. Raskin, P. Jutte, Sonia Cohen, S. Lozano-Calderón, O. Groot, J. H. Schwab   +10 more
semanticscholar   +1 more source

Predicting Skeletal-related Events Using SINS

Spine
Study Design. Predictive study utilized retrospectively collected data. Objective. The primary objective was to evaluate the predictive association between the Spine Instability Neoplastic Score (SINS) and Skeletal-related events (SREs).
Kazuo Nakanishi, Yasukazu Hijikata, Kazuya Uchino, Y. Sugimoto, Hideaki Iba, Seiya Watanabe, Shigeru Mitani   +6 more
semanticscholar   +1 more source

Bone metastases and skeletal-related events: incidence and prognosis according to histological subtype of lung cancer.

Future Oncology, 2019
AIM Estimate the incidence of bone metastases (BM) and skeletal-related events according to the histological subtype of lung cancer and its impact on patient survival.
G. T. Silva, L. M. Silva, A. Bergmann, L. Thuler   +3 more
semanticscholar   +1 more source

Examination of burden of skeletal-related events in patients naive to denosumab and intravenous bisphosphonate therapy in bone metastases from solid tumors population

Current Medical Research and Opinion, 2018
Objectives: Skeletal-related events (SREs), i.e. pathologic fractures, spinal cord compression, surgery and radiation to bone, are serious skeletal complications that occur frequently in patients with bone metastases (BMs) from solid tumors (STs ...
D. Bhowmik, Xue Song, M. Intorcia, S. Gray, N. Shi   +4 more
semanticscholar   +1 more source

An Italian survey on the use of denosumab for the management of skeletal-related events in patients with bone metastases.

European Review for Medical and Pharmacological Sciences, 2022
R. Berardi, A. Berruti, L. Brogelli, P. Zucali   +3 more
semanticscholar   +1 more source

Risk factors for skeletal-related events in patients with bone metastasis from breast cancer undergoing treatment with zoledronate

Breast Cancer Research and Treatment, 2020
H. Miyashita, Christina Cruz, S. Malamud
semanticscholar   +1 more source