Results 291 to 300 of about 386,289 (317)

Managing bone metastases and reducing skeletal related events in prostate cancer

Nature Reviews Clinical Oncology, 2014
Advanced-stage prostate cancer is associated with skeletal complications related to metastatic disease and its treatment. On the one hand, metastatic disease to bone is commonly associated with skeletal-related events (SREs); on the other hand, treatment with androgen-deprivation therapy (ADT) leads to loss in bone mineral density (BMD) and increased ...
Benjamin A, Gartrell, Fred, Saad
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Patients with SMARCA4-deficient thoracic sarcoma and severe skeletal-related events

Lung Cancer, 2019
SMARCA4-deficient thoracic sarcoma(DTS) is a recently identified new entity of thoracic malignancies characterized by inactivation of SMARCA4. Patients with SMARCA4-DTS have a particulary aggresive clinical course and no effective treatments. However, the detailed clinical features of SMARCA4-DTS remain unclear. Here, we report the clinical courses and
Kei Kunimasa, Harumi Nakamura, Kazuko Sakai, Motohiro Tamiya, Madoka Kimura, Takako Inoue, Kazumi Nishino, Hanako Kuhara, Shin-ichi Nakatsuka, Kazuto Nishio, Fumio Imamura, Toru Kumagai   +11 more
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Opioid Use Among Metastatic Prostate Cancer Patients With Skeletal-related Events

Clinical Therapeutics, 2016
The development of skeletal-related events (SREs) (pathologic fracture, need for surgery and/or radiation to bone, spinal cord compression, and hypercalcemia of malignancy) in metastatic prostate cancer (MPC) is associated with worsened pain and compromised quality of life. Opioids are frequently used throughout the course of SRE treatment.
Avin, Yaldo, Lonnie, Wen, Augustina, Ogbonnaya, Adriana, Valderrama, Jonathan, Kish, Michael, Eaddy, Charles, Kreilick, Krishna, Tangirala, Katarzyna, Shields   +8 more
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Canadian Health Care Institution Resource Utilization Resulting From Skeletal-Related Events

Hospital Practice, 2014
We describe the types of major institution health care resources consumed as a result of skeletal-related events (SREs) [ie, pathological fracture, bone surgery, radiation to bone, spinal cord compression].A retrospective multicenter chart review of cancer patients with bone metastases who experienced SREs was conducted.
Mohdhar J, Habib, Tazmin, Merali, Allan, Mills, Visal, Uon   +3 more
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[Predictive factors for skeletal-related events in lung cancer].

Revue des maladies respiratoires, 2020
Skeletal-related events (SRE) are common in patients with bone metastatic lung cancer and have a negative impact on quality of life and survival. The objective of this study is to identify predictive factors for SRE occurrence among this population.We conducted a 3-year retrospective study including 100 lung cancer patients with bone metastasis.Eighty ...
A, Villemain, B, Ribeiro Baptista, N, Paillot, M, Soudant, O, Menard, Y, Martinet, A, Tiotiu   +6 more
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Costs of multiple myeloma and associated skeletal-related events in The Netherlands

Expert Review of Pharmacoeconomics & Outcomes Research, 2004
Multiple myeloma causes significant skeletal morbidity (e.g., pain and pathologic fractures) resulting from osteolytic lesions, and the associated medical costs can be considerable. Therefore, the authors of this review conducted a retrospective cost analysis to quantify the medical costs associated with skeletal complications in patients treated for ...
Groot, MT (Martijn), Huijgens, PC, Uyl - de Groot, Carin, Wijermans, P   +3 more
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Impact of denosumab on skeletal-related events in solid tumors.

Journal of Clinical Oncology, 2018
e18754Background: Skeletal-related events (SRE) are frequent consequences of bone metastases from solid tumours like breast, prostate and lung.
Sridevi Rajeeve, Stuthi Perimbeti, Karan Jatwani, Rishi Shrivastav, Vivek Modi   +4 more
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Incidence of skeletal-related events (SREs) among prostate cancer patients.

Journal of Clinical Oncology, 2013
e16035 Background: Skeletal related events (SREs) occur in men with prostate cancer and may result from both bone metastases and exposure to androgen deprivation therapy (ADT). The objective of this study was to quantify the incidence of SREs in patients with prostate cancer treated with ADT or orchiectomy in clinical practice.
Marianne Ulcickas Yood, Teresa Maria Zyczynski, Karen Wells, Deborah Casso, Benjamin Gutierrez, Kimberley J. Woodcroft, Shinta Cheng   +6 more
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Skeletal-related events and mortality among older men with advanced prostate cancer

Journal of Geriatric Oncology, 2014
Skeletal-related events (SREs) are defined as a cluster of events including clinical diagnoses and treatment. Using claims data, the burden of SREs as a group has been reported among patients with cancer. We investigate the mortality impact of subcomponents of SREs, a topic that has received limited attention among older men.We analyzed prostate cancer
Eberechukwu, Onukwugha, Candice, Yong, C Daniel, Mullins, Brian, Seal, Diane, McNally, Arif, Hussain   +5 more
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Bone targeted therapy for preventing skeletal-related events in metastatic breast cancer

Bone, 2016
Cancer cells can alter physiological mechanisms within bone resulting in high bone turnover, and consequently in skeletal-related events (SREs), causing severe morbidity in affected patients. The goals of bone targeted therapy, as bisphosphonates and denosumab, are the reduction of incidence and the delay in occurrence of the SREs, to improve quality ...
IRELLI, AZZURRA, COCCIOLONE, VALENTINA, Cannita, Katia, Zugaro, Luigi, DI STASO, MARIO, Lanfiuti Baldi, Paola, PARADISI, STEFANIA, Sidoni, Tina, RICEVUTO, Enrico, FICORELLA, Corrado   +9 more
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