Results 151 to 160 of about 2,563,441 (411)

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

open access: yesAdvanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana   +4 more
wiley   +1 more source

Treatment with the anti-IL-6 receptor antibody attenuates muscular dystrophy via promoting skeletal muscle regeneration in dystrophin-/utrophin-deficient mice

open access: yesSkeletal Muscle, 2017
Background Chronic increases in the levels of the inflammatory cytokine interleukin-6 (IL-6) in serum and skeletal muscle are thought to contribute to the progression of muscular dystrophy.
Eiji Wada   +5 more
doaj   +1 more source

Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ

open access: yesTheranostics, 2018
The mechanism by which adipocyte-derived endocrine factors promote insulin resistance in skeletal muscle are not fully understood. MiR-27a is highly expressed in sera of obese individuals with prediabetes and T2DM, and mainly derived by adipose tissues ...
Yang Yu   +8 more
semanticscholar   +1 more source

Development of a Novel Device for the Perfusion Driven Decellularization of Skeletal Muscle [PDF]

open access: yes, 2014
Decellularization of skeletal muscle is a process that removes cellular components of skeletal muscle tissue while leaving behind the intact extracellular matrix (ECM).
Kasukonis, Benjamin
core   +2 more sources

A shared mechanism of muscle wasting in cancer and Huntington's disease. [PDF]

open access: yes, 2015
Skeletal muscle loss and dysfunction in aging and chronic diseases is one of the major causes of mortality in patients, and is relevant for a wide variety of diseases such as neurodegeneration and cancer.
Constantinou C   +4 more
core   +2 more sources

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee   +9 more
wiley   +1 more source

Implications of skeletal muscle loss for public health nutrition messages:a brief report [PDF]

open access: yes, 2015
Age-related skeletal muscle loss, sarcopenia, cachexia and wider malnutrition (under nutrition) are complex in aetiology with interaction of clinical, social and economic factors.
Levy, Louis B, Welch, Ailsa A
core   +1 more source

Rational Molecular Design of Aniline‐Based Donor‐Acceptor Conducting Polymers Enhancing Ionic Molecular Interaction for High‐Performance Wearable Bioelectronics

open access: yesAdvanced Healthcare Materials, EarlyView.
Organic conducting polymers are crucial for advanced wearable bioelectronic devices. A novel aniline‐based donor‐acceptor conducting polymer is developed via a rational molecular design approach, exhibiting enhanced ionic molecular interactions for highly sensitive and stable wearable pH sensors.
Junning Qian   +3 more
wiley   +1 more source

Regulation of DMD pathology by an ankyrin-encoded miRNA

open access: yesSkeletal Muscle, 2011
Background Duchenne muscular dystrophy (DMD) is an X-linked myopathy resulting from the production of a nonfunctional dystrophin protein. MicroRNA (miRNA) are small 21- to 24-nucleotide RNA that can regulate both individual genes and entire cell ...
Alexander Matthew S   +9 more
doaj   +1 more source

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